Mouse models for human intestinal microbiota research: a critical evaluation

F Hugenholtz, WM de Vos - Cellular and Molecular Life Sciences, 2018 - Springer
Since the early days of the intestinal microbiota research, mouse models have been used
frequently to study the interaction of microbes with their host. However, to translate the …

Microbiome–metabolome reveals the contribution of gut–kidney axis on kidney disease

YY Chen, DQ Chen, L Chen, JR Liu, ND Vaziri… - Journal of translational …, 2019 - Springer
Dysbiosis represents changes in composition and structure of the gut microbiome
community (microbiome), which may dictate the physiological phenotype (health or …

The human gut virome is highly diverse, stable, and individual specific

AN Shkoporov, AG Clooney, TDS Sutton, FJ Ryan… - Cell host & …, 2019 - cell.com
The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain
uncharacterized, and their roles in shaping the gut microbiome and in impacting on human …

Improvement of insulin sensitivity after lean donor feces in metabolic syndrome is driven by baseline intestinal microbiota composition

RS Kootte, E Levin, J Salojärvi, LP Smits, AV Hartstra… - Cell metabolism, 2017 - cell.com
The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor …

Applying the core microbiome to understand host–microbe systems

A Risely - Journal of Animal Ecology, 2020 - Wiley Online Library
The host‐associated core microbiome was originally coined to refer to common groups of
microbes or genes that were likely to be particularly important for host biological function …

Optimizing methods and dodging pitfalls in microbiome research

D Kim, CE Hofstaedter, C Zhao, L Mattei, C Tanes… - Microbiome, 2017 - Springer
Research on the human microbiome has yielded numerous insights into health and disease,
but also has resulted in a wealth of experimental artifacts. Here, we present suggestions for …

[HTML][HTML] Impacts of gut bacteria on human health and diseases

YJ Zhang, S Li, RY Gan, T Zhou, DP Xu… - International journal of …, 2015 - mdpi.com
Gut bacteria are an important component of the microbiota ecosystem in the human gut,
which is colonized by 10 14 microbes, ten times more than the human cells. Gut bacteria …

Gut microbiota diversity and human diseases: should we reintroduce key predators in our ecosystem?

A Mosca, M Leclerc, JP Hugot - Frontiers in microbiology, 2016 - frontiersin.org
Most of the Human diseases affecting westernized countries are associated with dysbiosis
and loss of microbial diversity in the gut microbiota. The Western way of life, with a wide use …

Findings from a randomized controlled trial of fecal transplantation for patients with ulcerative colitis

NG Rossen, S Fuentes, MJ van der Spek, JG Tijssen… - Gastroenterology, 2015 - Elsevier
Background & Aims Several case series have reported the effects of fecal microbiota
transplantation (FMT) for ulcerative colitis (UC). We assessed the efficacy and safety of FMT …

Biopsychosocial aspects of functional gastrointestinal disorders: how central and environmental processes contribute to the development and expression of functional …

L Van Oudenhove, RL Levy, MD Crowell… - Gastroenterology, 2016 - Elsevier
We provide a general framework for understanding functional gastrointestinal disorders
(FGIDs) from a biopsychosocial perspective. More specifically, we provide an overview of …