Survival in and colonization of the tsetse fly midgut are essential steps in the transmission of
many species of African trypanosomes. In the fly, bloodstream trypanosomes transform into …

Transmission of trypanosomatids to their mammalian hosts requires a complex series of
developmental transitions in their insect vectors, including stable attachment to an insect …

Tsetse flies (Glossina spp.) vector pathogenic African trypanosomes, which cause sleeping
sickness in humans and nagana in domesticated animals. Additionally, tsetse harbors 3 …

Savannah habitats comprise an ecologically important, but ultimately fragile, ecosystem.
They constitute one of the largest biomes on Earth, covering almost 20% of the land surface …

The cell surface of Trypanosoma brucei, like many protistan blood parasites, is crucial for
mediating host-parasite interactions and is instrumental to the initiation, maintenance and …

Tsetse-transmitted African trypanosomes must develop into mammalian-infectious
metacyclic cells in the fly's salivary glands (SGs) before transmission to a new host. The …

The tsetse fly vector transmits the protozoan Trypanosoma brucei, responsible for Human
African Trypanosomiasis, one of the most neglected tropical diseases. Despite a recent …

African trypanosomes, the causative agents of sleeping sickness in humans and nagana in
animals, have a complex digenetic life cycle between a mammalian host and an insect …

The agents of sleeping sickness disease, Trypanosoma brucei complex parasites, are
transmitted to mammalian hosts through the bite of an infected tsetse. Information on tsetse …

Trypanosoma brucei lives an entirely extracellular life cycle in its mammalian host, facing a
constant onslaught of host antibodies. The parasite evades clearance by the host immune …