Shikonin and its derivatives, isolated from traditional medicinal plant species of the genus
Lithospermum, Alkanna, Arnebia, Anchusa, Onosma, and Echium belonging to the …

Consumers' actual demand to be informed on the quality of food items during storage and
transportation drives researchers to focus on new and innovative systems with the ability to …

Background Colorectal cancer (CRC) is a malignant affliction that burdens people globally.
Overactivated Hedgehog signal is highly implicated in CRC pathogenesis. Phytochemical …

Malignant tumor, the leading cause of death worldwide, poses a serious threat to human
health. For decades, natural product has been proven to be an essential source for novel …

Background Shikonin, a natural naphthoquinone compound, has a wide range of
pharmacological effects, but its anti-tumor effect and underlying mechanisms in bladder …

The current synthetic plastic-based packaging creates environmental hazards that impact
climate change. Hence, the topic of the current research in food packaging is biodegradable …

Current pharmaceutical research is energetically excavating the pharmacotherapeutic role
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …

Shikonin and its derivatives are the natural naphthoquinone compounds produced in the
roots of the Boraginaceae family. These red pigments have been used for a long time in …

Background Shikonin (SKN), the main bioactive component isolated from Lithospermum
erythrorhizon Sieb et Zucc, has multiple activities including anti-rheumatic effect, but its …

Background Rheumatoid arthritis (RA) is a common chronic and systemic autoimmune
disease characterized by persistent inflammation and hyperplasia of the synovial …