Intermittent claudication (IC) is defined by leg muscle pain, cramping and fatigue brought on
by ambulation/exercise; relieved on rest; and caused by inadequate blood supply and is the …

Purpose Cardiovascular disease (CVD) is the leading cause of death worldwide. The
current CVD therapeutic drugs require long-term treatment with high doses, which increases …

Background: Statin dose guidelines for patients with peripheral artery disease (PAD) are
largely based on coronary artery disease and stroke data. The aim of this study is to …

OBJECTIVES: The Heart Protection Study (HPS) provides an opportunity to assess directly
the effects of cholesterol-lowering therapy on major vascular events (defined as myocardial …

Background The aim of the present study was to prospectively evaluate the sensitivity,
specificity, positive and negative likelihood ratios (LR+, LR-) of the ankle-brachial index …

OBJECTIVE: We investigated the usefulness of infrared thermography in evaluating patients
at high risk for lower extremity peripheral arterial disease (PAD), including severity …

D-dimers have been discovered as by-products of fibrinolysis. In situations where the
fundamental pathology is associated with increased thrombolytic activity, D-dimer assays …

Background Supervised exercise therapy (SET) is recommended as the primary treatment
for patients with intermittent claudication (IC). However, there is concern regarding the safety …

Peripheral artery disease (PAD) is associated with an increased risk for cardiovascular
events. D-dimers are a marker for hypercoagulability and are linked with thrombotic events …

Peripheral arterial disease (PAD) is a highly prevalent atherosclerotic condition. In patients
with PAD, the presence of intermittent claudication leads to a deterioration in quality of life. In …