Tumor necrosis factor-α (TNF-α) signaling is central to the transmission of the innate immune
response and subsequent activation of the adaptive immune system. The functioning of both …

Neisseria meningitidis, the causative agent of meningitis and septicemia, is able to attach to
and invade a variety of cell types. In a previous study we showed that entry of N. meningitidis …

Spleen tyrosine kinase (SYK) is a nonreceptor tyrosine kinase which associates directly with
extracellular receptors, and is critically involved in signal transduction pathways in a variety …

Cystic fibrosis (CF), a disease caused by mutations in the cystic fibrosis transmembrane
regulator (CFTR) chloride channel, is associated in the respiratory system with the …

Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances
in our understanding of membrane organization, with a particular focus on the cutting-edge …

Invasion of epithelial cells represents a potential pathogenic mechanism for Pseudomonas
aeruginosa. We explored the role of mitogen-activated protein kinase kinases (MEK 1/2) and …

Bacterial infections are the second-leading cause of death, globally. The prevalence of
antibacterial resistance has kept the demand strong for the development of new and potent …

The ocular surface usually looks quiet, presenting a general impression of biological
inactivity. Yet, the ability of the cornea to maintain health while continually exposed to …

Clinical isolates of Pseudomonas aeruginosa are either invasive or cytotoxic towards
mammalian epithelial cells, endothelial cells, and macrophages. Invasion requires host cell …

Diabetes mellitus (DM) is a chronic disease and a threatening problem for world health.
Allopathic medications are not efficient enough in controlling DM and its complications …