Ca2+ activated Cl− channels (CaCC) are up-regulated in cystic fibrosis (CF) airway surface
epithelia. The presence and functional properties of CaCC make it a possible therapeutic …

Pseudomonas aeruginosa is a major cause of hospital-acquired infections, and LecB, a
lectin that mediates bacterial attachment, biofilm formation, and virulence, is a key factor in …

The role of fibronectin (Fn) and its natural receptors α 5 β 1 integrins in the interaction of P.
aeruginosa with A549 epithelial cells was compared in the clinical isolate ER97314 and the …

Pseudomonas aeruginosa is a major cause of bacterial keratitis (BK) worldwide.
Inappropriate or non-optimal antibiotic chemotherapy can lead to corneal perforation and …

While a combination of mucosal defense defects in the Cystic Fibrosis (CF) lung allows for
the colonization by a range of opportunistic pathogens, the Gram-negative bacterium …

目的制备靶向铜绿假单胞菌(Pseudomonas aeruginosa) III 型分泌系统组件蛋白PcrV 的scFv-
Fc 形式的单克隆抗体MFa, 并研究其体外对铜绿假单胞菌生物膜形成及细胞黏附和侵入的影响 …

Pseudomonas aeruginosa is typically considered an opportunistic bacterial pathogen, only
affecting individuals with a compromised immune system. Despite the presence of a …

Pseudomonas aeruginosa is one of the key bacterial pathogens that cause acute, chronic,
and lethal infections in the lungs of patients with cystic fibrosis (CF). P. aeruginosa adheres …

Exposure to geogenic (earth-derived) particulate matter (PM) is linked to an increased
prevalence of bronchiectasis and other respiratory infections in Australian Indigenous …

Understanding how innocuous organisms can evolve to be pathogenic to humans is of
increasing global concern. Further, understanding how existing pathogens may evolved to …