Phenols in pharmaceuticals: analysis of a recurring motif

KA Scott, PB Cox, JT Njardarson - Journal of Medicinal Chemistry, 2022 - ACS Publications
Phenols and phenolic ethers are significant scaffolds recurring both in nature and among
approved small-molecule pharmaceuticals. This compendium presents the first …

[HTML][HTML] The effectiveness of virtual reality in managing acute pain and anxiety for medical inpatients: systematic review

V Smith, RR Warty, JA Sursas, O Payne, A Nair… - Journal of medical …, 2020 - jmir.org
Background: Virtual reality is increasingly being utilized by clinicians to facilitate analgesia
and anxiolysis within an inpatient setting. There is however, a lack of a clinically relevant …

Modeling health benefits and harms of public policy responses to the US opioid epidemic

AL Pitt, K Humphreys… - American journal of …, 2018 - ajph.aphapublications.org
Objectives. To estimate health outcomes of policies to mitigate the opioid epidemic.
Methods. We used dynamic compartmental modeling of US adults, in various pain, opioid …

Association between US state medical cannabis laws and opioid prescribing in the Medicare Part D population

AC Bradford, WD Bradford, A Abraham… - JAMA internal …, 2018 - jamanetwork.com
Importance Opioid-related mortality increased by 15.6% from 2014 to 2015 and increased
almost 320% between 2000 and 2015. Recent research finds that the use of all pain …

Understanding the rural–urban differences in nonmedical prescription opioid use and abuse in the United States

KM Keyes, M Cerdá, JE Brady… - … journal of public …, 2014 - ajph.aphapublications.org
Nonmedical prescription opioid misuse remains a growing public problem in need of action
and is concentrated in areas of US states with large rural populations such as Kentucky …

[HTML][HTML] Pain management during the COVID-19 pandemic

SN El-Tallawy, R Nalamasu, JV Pergolizzi, C Gharibo - Pain and Therapy, 2020 - Springer
Chronic pain management during the coronavirus disease 2019 (COVID-19) pandemic is a
challenging process, especially with growing evidence that COVID-19 infection is …

Societal costs of prescription opioid abuse, dependence, and misuse in the United States

HG Birnbaum, AG White, M Schiller, T Waldman… - Pain …, 2011 - academic.oup.com
Objectives. The objective of this study was to estimate the societal costs of prescription
opioid abuse, dependence, and misuse in the United States. Methods. Costs were grouped …

[HTML][HTML] The impact of virtual reality on chronic pain

T Jones, T Moore, J Choo - PloS one, 2016 - journals.plos.org
The treatment of chronic pain could benefit from additional non-opioid interventions. Virtual
reality (VR) has been shown to be effective in decreasing pain for procedural or acute pain …

Opioids and cardiac arrhythmia: a literature review

M Behzadi, S Joukar, A Beik - Medical principles and practice, 2018 - karger.com
Objective: One of the most important side effects of opioids is their influence on the electrical
activity of the heart. This review focusses on the effects of opioids on QT interval …

The downward spiral of chronic pain, prescription opioid misuse, and addiction: cognitive, affective, and neuropsychopharmacologic pathways

EL Garland, B Froeliger, F Zeidan, K Partin… - Neuroscience & …, 2013 - Elsevier
Prescription opioid misuse and addiction among chronic pain patients are emerging public
health concerns of considerable significance. Estimates suggest that more than 10% of …