Synthetic nanoparticles for vaccines and immunotherapy

DJ Irvine, MC Hanson, K Rakhra, T Tokatlian - Chemical reviews, 2015 - ACS Publications
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape

C Zylberberg, S Matosevic - Drug delivery, 2016 - Taylor & Francis
Liposomes were the first nanoscale drug to be approved for clinical use in 1995. Since then,
the technology has grown considerably, and pioneering recent work in liposome-based …

The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells

V Dartois - Nature Reviews Microbiology, 2014 - nature.com
For the successful treatment of pulmonary tuberculosis, drugs need to penetrate complex
lung lesions and permeate the mycobacterial cell wall in order to reach their intracellular …

Nanotechnology and pulmonary delivery to overcome resistance in infectious diseases

F Andrade, D Rafael, M Videira, D Ferreira… - Advanced drug delivery …, 2013 - Elsevier
Used since ancient times especially for the local treatment of pulmonary diseases, lungs and
airways are a versatile target route for the administration of both local and systemic drugs …

[HTML][HTML] Rational design of liposomal drug delivery systems, a review: Combined experimental and computational studies of lipid membranes, liposomes and their …

A Bunker, A Magarkar, T Viitala - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Combined experimental and computational studies of lipid membranes and liposomes, with
the aim to attain mechanistic understanding, result in a synergy that makes possible the …

[HTML][HTML] Novel drug delivery systems targeting oxidative stress in chronic obstructive pulmonary disease: a review

Y Xu, H Liu, L Song - Journal of nanobiotechnology, 2020 - Springer
Oxidative stress is significantly involved in the pathogenesis and progression of chronic
obstructive pulmonary disease (COPD). Combining antioxidant drugs or nutrients results in …

Mucoadhesive chitosan-coated solid lipid nanoparticles for better management of tuberculosis

ACC Vieira, LL Chaves, S Pinheiro, S Pinto… - International journal of …, 2018 - Elsevier
Taking into consideration the potential mucoadhesion properties of systems in lung delivery,
this paper describes the preparation and characterization of chitosan-coated solid lipid …

[HTML][HTML] Recent developments and applications of smart nanoparticles in biomedicine

S Campora, G Ghersi - Nanotechnology Reviews, 2022 - degruyter.com
Over the last decades, nanotechnology applied in medicine (nanomedicine) has sparked
great interest from the scientific community, thanks to the possibility to engineer …

The formulation of nanomedicines for treating tuberculosis

A Costa, M Pinheiro, J Magalhães, R Ribeiro… - Advanced drug delivery …, 2016 - Elsevier
Recent estimates indicate that tuberculosis (TB) is the leading cause of death worldwide,
alongside the human immunodeficiency virus (HIV) infection. The current treatment is …

Recent advances in ultrasound-triggered drug delivery through lipid-based nanomaterials

A Ahmadi, S Hosseini-Nami, Z Abed, J Beik… - Drug Discovery …, 2020 - Elsevier
Highlights•The side effects on healthy tissue are of drawbacks of cancer chemotherapy.•
Nanocarriers to transport of chemotherapeutics into the tumor are an ideal scenario.• …