Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology

N Bakeer, J James, S Roy… - Proceedings of the …, 2016 - National Acad Sciences
Cardiopulmonary complications are the leading cause of mortality in sickle cell anemia
(SCA). Elevated tricuspid regurgitant jet velocity, pulmonary hypertension, diastolic, and …

Characterising the myocardial interstitial space: the clinical relevance of non-invasive imaging

SK White, DM Sado, AS Flett, JC Moon - Heart, 2012 - heart.bmj.com
The myocardial interstitial or extracellular space exists as a complex and dynamic
environment, vital for normal cardiac structure and function. The physiological pathways for …

Assessment of diffuse myocardial fibrosis in rats using small-animal Look-Locker inversion recovery T1 mapping

DR Messroghli, S Nordmeyer, T Dietrich… - Circulation …, 2011 - Am Heart Assoc
Background—The concentration of gadopentetate dimeglumine in myocardium and blood
can be assessed from T1 measurements and can be used to calculate the extracellular …

Myocardial T1 mapping for detection of left ventricular myocardial fibrosis in chronic aortic regurgitation: pilot study

P Sparrow, DR Messroghli, S Reid… - American Journal of …, 2006 - Am Roentgen Ray Soc
OBJECTIVE. The aim of this study was to identify diffuse myocardial fibrosis secondary to
chronic aortic regurgitation by comparing the T1 relaxation times of left ventricular …

T1 and T2 mapping cardiovascular magnetic resonance imaging techniques reveal unapparent myocardial injury in patients with myocarditis

UK Radunski, GK Lund, D Säring, S Bohnen… - Clinical research in …, 2017 - Springer
Introduction This study evaluated the ability of T1 and T2 mapping cardiovascular magnetic
resonance (CMR) to detect myocardial injury in apparently normal myocardium of patients …

The influence of myocardial blood flow and volume of distribution on late Gd‐DTPA kinetics in ischemic heart failure

C Klein, SG Nekolla, T Balbach… - Journal of Magnetic …, 2004 - Wiley Online Library
Purpose To determine the mechanism of enhancement of contrast‐enhanced MRI (ceMRI)
in chronic ischemic myocardium. While ceMRI can identify scar tissue in chronic ischemic …

Comprehensive cardiovascular magnetic resonance tissue characterization and cardiotoxicity in women with breast cancer

P Thavendiranathan, T Shalmon, CPS Fan… - JAMA …, 2023 - jamanetwork.com
Importance There is a growing interest in understanding whether cardiovascular magnetic
resonance (CMR) myocardial tissue characterization helps identify risk of cancer therapy …

T1 mapping: characterisation of myocardial interstitial space

RJ Perea, JT Ortiz-Perez, M Sole, MT Cibeira… - Insights into …, 2015 - Springer
Myocardial fibrosis is always present in end-stage heart failure and is a major independent
predictor of adverse cardiac outcome. Cardiac magnetic resonance (CMR) is an imaging …

Adaptive registration of varying contrast‐weighted images for improved tissue characterization (ARCTIC): Application to T1 mapping

S Roujol, M Foppa, S Weingärtner… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To propose and evaluate a novel nonrigid image registration approach for
improved myocardial T1 mapping. Methods Myocardial motion is estimated as global affine …

[HTML][HTML] Cardiac magnetic resonance T1 mapping. Part 1: Aspects of acquisition and evaluation

G Reiter, C Reiter, C Kräuter, M Fuchsjäger… - European journal of …, 2018 - Elsevier
While an enormous number of studies have documented pathological alterations of the
myocardial native longitudinal relaxation time (T1) and the fraction of the extracellular …