[HTML][HTML] Viral vector-based gene therapy
X Li, Y Le, Z Zhang, X Nian, B Liu, X Yang - International Journal of …, 2023 - mdpi.com
Gene therapy is a technique involving the modification of an individual's genes for treating a
particular disease. The key to effective gene therapy is an efficient carrier delivery system …
particular disease. The key to effective gene therapy is an efficient carrier delivery system …
[HTML][HTML] Appraisal for the potential of viral and nonviral vectors in gene therapy: A review
Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …
[HTML][HTML] Cell-penetrating peptide-based delivery of macromolecular drugs: development, strategies, and progress
Z Sun, J Huang, Z Fishelson, C Wang, S Zhang - Biomedicines, 2023 - mdpi.com
Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being
extensively studied due to their excellent delivery performance. Compared with other …
extensively studied due to their excellent delivery performance. Compared with other …
Expression of codon-optimized PDCoV-RBD protein in baculovirus expression system and immunogenicity evaluation in mice
N Wang, Z Wang, M Ma, X Jia, H Liu, M Qian… - International Journal of …, 2023 - Elsevier
Porcine deltacoronavirus (PDCoV) is a global epidemic enteropathogenic coronavirus that
mainly infects piglets, and causes huge losses to the pig industry. However, there are still no …
mainly infects piglets, and causes huge losses to the pig industry. However, there are still no …
[HTML][HTML] Solutions against emerging infectious and noninfectious human diseases through the application of baculovirus technologies
AM Targovnik, JA Simonin, GJ Mc Callum… - Applied microbiology …, 2021 - Springer
Baculoviruses are insect pathogens widely used as biotechnological tools in different fields
of life sciences and technologies. The particular biology of these entities (biosafety viruses 1; …
of life sciences and technologies. The particular biology of these entities (biosafety viruses 1; …
Engineering strategies for insect viruses and microbes for dsRNA production and delivery to insects for targeted gene silencing
Q Xue, É Avila dos Santos, G Smagghe… - Entomologia …, 2023 - biblio.ugent.be
RNA interference (RNAi)-based pest control is viewed as a safe and effective method for
insect pest control. However, the stability and efficient cellular delivery of the double …
insect pest control. However, the stability and efficient cellular delivery of the double …
Genetically modified cell sheets in regenerative medicine and tissue engineering
Z Jiang, N Li, D Zhu, L Ren, Q Shao, K Yu, G Yang - Biomaterials, 2021 - Elsevier
Genetically modified cell sheet technology is emerging as a promising biomedical tool to
deliver therapeutic genes for regenerative medicine and tissue engineering. Virus-based …
deliver therapeutic genes for regenerative medicine and tissue engineering. Virus-based …
[HTML][HTML] Investigation and restoration of BEST1 activity in patient-derived RPEs with dominant mutations
Abstract BEST1 is a Ca2+-activated Cl− channel predominantly expressed in retinal pigment
epithelium (RPE), and over 250 genetic mutations in the BEST1 gene have been identified …
epithelium (RPE), and over 250 genetic mutations in the BEST1 gene have been identified …
Baculovirus as versatile vectors for protein display and biotechnological applications
CH Tsai, SC Wei, HR Lo, YC Chao - Current issues in molecular biology, 2019 - mdpi.com
The baculovirus-insect cell system has long been deployed for a variety of applications
including for use as biopesticides, for recombinant protein production, transient transgene …
including for use as biopesticides, for recombinant protein production, transient transgene …
[HTML][HTML] Methods of miRNA delivery and possibilities of their application in neuro-oncology
I Gareev, O Beylerli, T Rasim, T Ilyasova… - Non-coding RNA …, 2023 - Elsevier
In the current phase of medical progress, practical neuro-oncology faces critical challenges.
These include the quest for and development of innovative methodological approaches, as …
These include the quest for and development of innovative methodological approaches, as …