T cells in ocular autoimmune uveitis: Pathways and therapeutic approaches

M Zhang, X Zhang - International Immunopharmacology, 2023 - Elsevier
Autoimmune uveitis is a non-infectious intraocular condition that affects the uveal tract of the
eye and threatens vision if not treated properly. Increasing evidence suggests that activated …

cAMP: A master regulator of cadherin‐mediated binding in endothelium, epithelium and myocardium

F Vielmuth, MY Radeva, S Yeruva… - Acta …, 2023 - Wiley Online Library
Regulation of cadherin‐mediated cell adhesion is crucial not only for maintaining tissue
integrity and barrier function in the endothelium and epithelium but also for …

[PDF][PDF] Microbiome and Behçet's disease: a systematic review

M Joubert, M André, N Barnich, E Billard - Clin Exp Rheumatol, 2023 - behcetsuk.org
The aim of this review was to describe the changes in the microbiota of patients with
Behçet's disease (BD) and the mechanisms involved in the relationship between the …

[HTML][HTML] Oral Lesions as the Primary Manifestations of Behçet's Disease: The Importance of Interdisciplinary Diagnostics—A Case Report

AC Soares, FR Pires, NR de Oliveira Quintanilha… - Biomedicines, 2023 - mdpi.com
Background: Behçet's disease (BD) is a rare chronic auto-inflammatory systemic disease
with non-specific oral manifestations, categorised as generalised variable vessel vasculitis …

[HTML][HTML] The role of miRNAs in Behçet's disease

F Gu, X Huang, W Huang, M Zhao, H Zheng… - Frontiers in …, 2023 - frontiersin.org
The symptoms of Behçet's disease (BD), a multisystemic condition with autoimmune and
inflammation as hallmarks, include arthritis, recurring oral and vaginal ulcers, skin rashes …

[HTML][HTML] The roles of immune cells in Behçet's disease

D Hu, JL Guan - Advances in Rheumatology, 2023 - SciELO Brasil
Behçet's disease (BD) is a systemic vasculitis that can affect multiple systems, including the
skin, mucous membranes, joints, eyes, gastrointestinal and nervous. However, the …

Comprehensive analysis of T‐cell receptor repertoires reveals antigen‐driven T‐cell clusters in patients with Behçet's syndrome

J Zou, B Li, D Li, H Bao, C She, J Ye… - European Journal of …, 2023 - Wiley Online Library
T lymphocytes are the major components of adaptive immunity in Behçet's syndrome (BS)
pathology. However, the precise mechanism of T‐cell‐induced inflammatory condition …

[HTML][HTML] Unraveling the microbiome-metabolome nexus: a comprehensive study protocol for personalized management of Behçet's disease using explainable artificial …

S Tangaro, G Lopalco, D Sabella, V Venerito… - Frontiers in …, 2024 - frontiersin.org
The presented study protocol outlines a comprehensive investigation into the interplay
among the human microbiota, volatilome, and disease biomarkers, with a specific focus on …

[HTML][HTML] Kurarinone regulates Th17/Treg balance and ameliorates autoimmune uveitis via Rac1 inhibition

C Gu, Y Liu, J Lv, C Zhang, Z Huang, Q Jiang… - Journal of Advanced …, 2024 - Elsevier
Introduction Autoimmune uveitis (AU) is a severe intraocular autoimmune disorder with a
chronic disease course and a high rate of blindness. Kurarinone (KU), a major component of …

[HTML][HTML] Surgical management of aortic regurgitation secondary to Behcet's disease

HO Hu, CH Zhang, C Spadaccio, B Tang… - Frontiers in …, 2023 - frontiersin.org
Background Aortic regurgitation (AR) related to Behcet's disease (BD) is rare, but usually
fatal. Perivalvular leakage (PVL) is high if AR related to BD treated with regular AVR. In this …