Background Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal
dosing regimen remains unclear. We undertook a systematic review and individual patient …

Background The optimal dosing of primaquine to prevent relapsing Plasmodium vivax
malaria in South Asia remains unclear. We investigated the efficacy and safety of different …

Summary Background Prevention of Plasmodium vivax malaria recurrence is essential for
malaria elimination in Brazil. We evaluated the real-world effectiveness of an updated …

The escalating challenge of malaria control necessitates innovative approaches that extend
beyond traditional control strategies. This review explores the incorporation of traditional …

A single 300 mg dose of tafenoquine (an 8-aminoquinoline), in combination with a standard
3-day course of chloroquine, is approved in several countries for the radical cure (prevention …

Designing policy in public health is a complex process requiring decision making that
incorporates available evidence and is suitable to a country's epidemiological and health …

Primaquine dose and the risk of haemolysis and Plasmodium vivaxrecurrence: pooling the
available data to reassure the unconvinced 71 years after its US Food and Drug …

Plasmodium vivax and zoonotic Plasmodium knowlesi infections being co-endemic and
transmitted by 19 major vector species, and focused in hard-to-reach areas and populations …

[eng] INTRODUCTION: Papua New Guinea (PNG) has the highest malaria transmission
rates in the Pacific region. The Lihir Islands of PNG comprise the islands of Aniolam, where …

Background: Plasmodium vivax forms dormant liver stages (hypnozoites) that can reactivate
weeks to months after primary infection. Effective treatment requires a combination of …