[HTML][HTML] Surface design of nanocarriers: Key to more efficient oral drug delivery systems

H Spleis, M Sandmeier, V Claus… - Advances in colloid and …, 2023 - Elsevier
As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

The influence of nanoparticle properties on oral bioavailability of drugs

Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …

[HTML][HTML] Nanomedicine for increasing the oral bioavailability of cancer treatments

A Parodi, P Buzaeva, D Nigovora, A Baldin… - Journal of …, 2021 - Springer
Oral administration is an appealing route of delivering cancer treatments. However, the
gastrointestinal tract is characterized by specific and efficient physical, chemical, and …

Current development of cabazitaxel drug delivery systems

B Sun, JF Lovell, Y Zhang - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
The second‐generation taxane cabazitaxel has been clinically approved for the treatment of
metastatic castration‐resistant prostate cancer after docetaxel failure. Compared with the …

Protein corona liposomes achieve efficient oral insulin delivery by overcoming mucus and epithelial barriers

A Wang, T Yang, W Fan, Y Yang, Q Zhu… - Advanced …, 2019 - Wiley Online Library
Oral delivery of peptide/protein drugs has attracted worldwide attention due to its good
patient compliance and convenience of administration. Orally administered nanocarriers …

A probiotic spore‐based oral autonomous nanoparticles generator for cancer therapy

Q Song, C Zheng, J Jia, H Zhao, Q Feng… - Advanced …, 2019 - Wiley Online Library
Spores, the dormant life forms of probiotics, can germinate to metabolically active vegetative
cells with the disintegration of their hydrophobic protein coat in the intestinal …

Hydrogen-bonded tannic acid-based anticancer nanoparticle for enhancement of oral chemotherapy

Z Le, Y Chen, H Han, H Tian, P Zhao… - … applied materials & …, 2018 - ACS Publications
Oral chemotherapy has been emerging as a hopeful therapeutic regimen for the treatment of
various cancers because of its high safety and convenience, lower costs, and high patient …

[HTML][HTML] Gut microbiota as an “invisible organ” that modulates the function of drugs

X Li, L Liu, Z Cao, W Li, H Li, C Lu, X Yang… - Biomedicine & …, 2020 - Elsevier
Gut microbiota plays an important role in the gut and have become a hotspot of recent
research interests. Commensal microbiota in gut exert a variety of effects on the host, from …

Temperature-and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels

M Yu, W Song, F Tian, Z Dai, Q Zhu… - Proceedings of the …, 2019 - National Acad Sciences
Lipid nanovesicles are widely present as transport vehicles in living organisms and can
serve as efficient drug delivery vectors. It is known that the size and surface charge of …

Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease

C Chen, A Beloqui, Y Xu - Advanced drug delivery reviews, 2023 - Elsevier
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …