The loss of germ cells and spermatogenic failure in non-obstructive azoospermia are
believed to be the main causes of male infertility. Laboratory studies have used in vitro …

Sertoli cells contribute to the formation of the blood-testis barrier (BTB), which is necessary
for normal spermatogenesis. Recently, microRNAs (miRNAs) have emerged as …

Quercetin and kaempferol are flavonoids widely present in fruits, vegetables, and medicinal
plants. They have attracted much attention due to their antioxidant, anti-inflammatory …

Spermatogenesis holds considerable promise for human-assisted reproduction and
livestock breeding based on stem cells. It occurs in seminiferous tubules within the testis …

Chromium (Cr) and its compounds are closely associated with individuals' lives and
extensively used in industry. Excessive exposure to hexavalent chromium (Cr (VI)) induces …

Spermatogenesis is a highly organized process by which undifferentiated spermatogonia
self‐renew and differentiate into spermatocytes and spermatids. The entire developmental …

Abstract Di (2-ethylhexyl) phthalate (DEHP), identified as an endocrine-disrupting chemical,
is associated with reproductive toxicity. This association is particularly noteworthy in …

In vitro spermatogenesis (IVS) has important applications including fertility preservation of
prepubertal cancer patients; however, thus far, IVS has only been achieved using mouse …

Deleted in azoospermia-like (DAZL) is essential for mammalian testicular function and
spermatogenesis. To explore the molecular characterization, expression patterns, and …

Genomic integrity is critical for sexual reproduction, ensuring correct transmission of parental
genetic information to the descendant. To preserve genomic integrity, germ cells have …