The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an
obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful …

Among the different infective stages that Trypanosoma cruzi employs to invade cells,
extracellular amastigotes (EAs) have recently gained attention by our group. This is true …

Chagas disease, an illness caused by the protozoan Trypanosoma cruzi, is clinically and
epidemiologically important in Latin America, and particularly in Brazil. This article presents …

Numerous works have demonstrated that trypanosomatid motility is relevant for parasite
replication and sensitivity. Nonetheless, although some findings indirectly suggest that …

Introduction: Chagas disease is the highest impact human infectious disease in Latin
America, and the leading worldwide cause of myocarditis. Despite the availability of several …

The mechanisms by which Trypanosoma cruzi survives antimicrobial peptides and
differentiates during its transit through the gastrointestinal tract of the reduviid vector are …

The synthesis, antitrypanosomal, and cytotoxic activities of 17 furanchalcone derivatives are
described herein. The structure of the synthesized products was elucidated by a …

Trypanosoma cruzi has many molecules that need metallic elements to work, allowing cell
invasion and the establishment of infection, causing Chagas disease. Nonetheless …

Eukaryotic tRNAs, transcribed by RNA polymerase III (Pol III), contain boxes A and B as
internal promoter elements. One exception is the selenocysteine (Sec) tRNA (tRNA-Sec) …

In a recent work we demonstrated that Trypanosoma cruzi trypomastigotes change their
motility patterns in the presence of mammalian cells, that the extent of the changes depends …