Hypertension, the leading risk factor for cardiovascular disease, originates from combined
genetic, environmental, and social determinants. Environmental factors include …

As early as the 1920s, and subsequently in the 1959 Build and Blood Pressure Study (S1. 5-
1) of almost 5 million adults insured between 1934 and 1954, a strong direct relationship …

Background The relations of hypertension onset age with cardiovascular diseases (CVD)
and all-cause mortality remain inconclusive. Objectives This study sought to examine the …

Preeclampsia and gestational hypertension are common pregnancy complications
associated with adverse maternal and child outcomes. Current tools for prediction …

The known genetic architecture of blood pressure now comprises> 30 genes, with rare
variants resulting in monogenic forms of hypertension or hypotension and> 1,477 common …

Short chain fatty acid (SCFA) metabolites are byproducts of gut microbial metabolism that
are known to affect host physiology via host G protein-coupled receptor (GPCRs). We …

Cardiovascular disease is a leading cause of death worldwide and accounts for> 17.3
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …

Hypertension is an independent and preventable risk factor for the development of
cardiovascular diseases, however, little is known about the impact of gut microbiota …

The epithelial sodium channel (ENaC) is composed of three homologous subunits and
allows the flow of Na+ ions across high resistance epithelia, maintaining body salt and water …

Executive summary Elevated blood pressure is the strongest modifiable risk factor for
cardiovascular disease worldwide. Despite extensive knowledge about ways to prevent as …