1.1. Brief Historical Overview As expected from the fluorine position on the periodic table of
elements, it possesses some extreme properties, in particular, ultimate electronegativity and …

Abstract β-Adrenoceptor antagonists (β-blockers) have historically been considered an
effective and safe option for first-line treatment of hypertension. However, very recently, it …

High level of circulating red cell distribution width (RDW) and neutrophil/lymphocyte (N/L)
ratio may reflect ongoing vascular inflammation and play an important role in …

Abstract Purpose of Review Current guidelines for the management of arterial hypertension
endorse β-adrenergic receptor blocking agents (beta-blockers, BBs) as being particularly …

Hypertension is one of the leading risk factors for morbidity and mortality in patients with
cardiovascular and cerebrovascular diseases and renal impairment. It also leads to target …

Antitumor drugs have long been known to introduce a measurable risk of cardiovascular
events. Cardio-Oncology is the discipline that builds on collaboration between cardiologists …

Nebivolol is a racemic combination of d‐nebivolol (+ SRRR nebivolol) and l‐nebivolol (–
RSSS nebivolol) that differs chemically from other β‐blockers, with an absolutely …

Nebivolol is a third-generation β-adrenergic receptor antagonist (β-blocker) with high
selectivity for β 1-adrenergic receptors. In addition, it causes vasodilatation via interaction …

In this study, the Nsp12–Nsp8 complex of SARS-CoV-2 was targeted with structure-based
and computer-aided drug design approach because of its vital role in viral replication …

Background The major clinical problem of Marfan syndrome (MFS) is the aortic root
aneurysm, with risk of dissection when the root diameter approximates 5 cm. In MFS, a key …