Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …

The human innate and adaptive immune systems consist of effector cells producing
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …

The morbidity associated with neurodegenerative diseases (NDs) is increasing, posing a
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …

Obesity and insulin resistance are the major predisposing factors to comorbidities, such as
Type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative …

The importance of chronic low-grade inflammation in the pathology of numerous age-related
chronic conditions is now clear. An unresolved inflammatory response is likely to be …

Toll-like receptors (TLRs) belong to the pattern recognition receptor (PRR) family, a key
component of the innate immune system. TLRs detect invading pathogens and initiate an …

T-cell trafficking at vascular sites has emerged as a key step in antitumour immunity.
Chemokines are credited with guiding the multistep recruitment of CD8+ T cells across …

Inflammation is believed to play a central role in many of the chronic diseases that
characterize modern society. In the past decade, our understanding of how dietary fats affect …

Sutterella species have been frequently associated with human diseases, such as autism,
Down syndrome, and inflammatory bowel disease (IBD), but the impact of these bacteria on …

The incidence of hyperuricemia (HUA) and gout continuously increases and has become a
major public health problem. The gut microbiota, which colonizes the human intestine, has a …