Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss

S Quenby, ID Gallos, RK Dhillon-Smith, M Podesek… - The Lancet, 2021 - thelancet.com
Miscarriage is generally defined as the loss of a pregnancy before viability. An estimated 23
million miscarriages occur every year worldwide, translating to 44 pregnancy losses each …

Environmental factors in declining human fertility

NE Skakkebæk, R Lindahl-Jacobsen… - Nature Reviews …, 2022 - nature.com
A severe decline in child births has occurred over the past half century, which will lead to
considerable population declines, particularly in industrialized regions. A crucial question is …

Recurrent pregnancy loss

E Dimitriadis, E Menkhorst, S Saito… - Nature reviews disease …, 2020 - nature.com
Recurrent pregnancy loss is a distressing pregnancy disorder experienced by~ 2.5% of
women trying to conceive. Recurrent pregnancy loss is defined as the failure of two or more …

Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind, multicentre, randomised, placebo-controlled, phase 3 trial

M Schneider, M Narciso-Abraham, S Hadl, R McMahon… - The Lancet, 2023 - thelancet.com
Background VLA1553 is a live-attenuated vaccine candidate for active immunisation and
prevention of disease caused by chikungunya virus. We report safety and immunogenicity …

Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study

MC Magnus, AJ Wilcox, NH Morken, CR Weinberg… - bmj, 2019 - bmj.com
Objectives To estimate the burden of miscarriage in the Norwegian population and to
evaluate the associations with maternal age and pregnancy history. Design Prospective …

Eculizumab in paroxysmal nocturnal haemoglobinuria and atypical haemolytic uraemic syndrome: 10‐year pharmacovigilance analysis

G Socié, MP Caby‐Tosi, JL Marantz… - British journal of …, 2019 - Wiley Online Library
Eculizumab is the first and only medication approved for paroxysmal nocturnal
haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS) treatment …

SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during …

N Balachandren, MC Davies, JA Hall… - Human …, 2022 - academic.oup.com
STUDY QUESTION Does maternal infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) in the first trimester affect the risk of miscarriage before 13 …

The interplay between reproductive tract microbiota and immunological system in human reproduction

S Al-Nasiry, E Ambrosino, M Schlaepfer… - Frontiers in …, 2020 - frontiersin.org
In the last decade, the microbiota, ie, combined populations of microorganisms living inside
and on the surface of the human body, has increasingly attracted attention of researchers in …

Progestogens for preventing miscarriage: a network meta‐analysis

AJ Devall, A Papadopoulou, M Podesek… - Cochrane Database …, 2021 - cochranelibrary.com
Background Miscarriage, defined as the spontaneous loss of a pregnancy before 24 weeks'
gestation, is common with approximately 25% of women experiencing a miscarriage in their …

US Population-Based background incidence rates of medical conditions for use in safety assessment of COVID-19 vaccines

D Gubernot, A Jazwa, M Niu, J Baumblatt, J Gee… - Vaccine, 2021 - Elsevier
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has had a devastating
impact on global health, and has resulted in an unprecedented, international collaborative …