Nuclear factor κB (NF-κB) is a family of inducible transcription factors that plays a vital role in
different aspects of immune responses. NF-κB is normally sequestered in the cytoplasm as …

Chronic and acute renal diseases, irrespective of the initiating cause, have inflammation and
immune system activation as a common underlying mechanism. The purpose of this review …

The NF-κB family of transcription factors regulates the induction and resolution of
inflammation. Two main pathways, classical and alternative, control the nuclear …

Kidney diseases are major health problem and understanding the underlined mechanisms
that lead to kidney diseases are critical research points with a marked potential impact on …

Systemic lupus erythematosus (SLE) is a heterogeneous group of autoimmune disorders
defined by a consensus of clinical and laboratory criteria. Much of the pathophysiology and …

Oxidative stress and inflammation contribute importantly to the pathogenesis of chronic
kidney disease (CKD). Epigallocatechin‐3‐gallate (EGCG), which is the most abundant and …

Physiological Glucocorticoids are important regulators of the immune system.
Pharmacological GCs are in widespread use to treat inflammatory diseases. Adrenalectomy …

Acute kidney injury (AKI) is a common and potentially life-threatening complication after
ischemia/reperfusion and exposure to nephrotoxic agents. In this study, we examined the …

Inflammatory pathways are activated in most glomerular diseases but molecular
mechanisms driving them in kidney tissue are poorly known. We identified retinoic acid …

The genetic factors underlying the pathogenesis of lupus nephritis associated with systemic
lupus erythematosus are largely unknown, although animal studies indicate that nuclear …