Abstract Endothelial–mesenchymal transition (EndoMT), a cellular differentiation process in
which endothelial cells (ECs) lose their properties and differentiate into mesenchymal cells …

Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …

Disruption of pulmonary vascular homeostasis is a central feature of viral pneumonia,
wherein endothelial cell (EC) death and subsequent angiogenic responses are critical …

Transcription factors, extensively described for their role in epithelial–mesenchymal
transition (EMT-TFs) in epithelial cells, also display essential functions in the melanocyte …

Background The efficacy of immunotherapies in metastatic melanoma depends on a robust
T cell infiltration. Oncogenic alterations of tumor cells have been associated to T cell …

Zinc finger E-box binding homeobox 1 (ZEB1) is a master modulator of the epithelial–
mesenchymal transition (EMT), a process whereby epithelial cells undergo a series of …

Background: Cardiac fibrosis is a lethal outcome of excessive formation of myofibroblasts
that are scar-forming cells accumulated after heart injury. It has been reported that cardiac …

The immunosuppressive and hypoxic tumor microenvironment (TME) remains a major
obstacle to impede cancer immunotherapy. Here, we showed that elevated levels of Delta …

Nanomedicines for antitumour therapy have been widely studied in recent decades, but only
a few have been used in clinical applications. One of the most important reasons is the poor …

Background Non-small cell lung cancer (NSCLC) accounts for about 80–85% of total lung
cancer cases. Identifying the molecular mechanisms of anti-tumor drugs is essential for …