Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities
R Kumar, Ö Aktay-Cetin, V Craddock… - PLoS …, 2023 - journals.plos.org
The Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to healthcare …
Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to healthcare …
Human Lung Organoids—A Novel Experimental and Precision Medicine Approach
L Kühl, P Graichen, N von Daacke, A Mende… - Cells, 2023 - mdpi.com
The global burden of respiratory diseases is very high and still on the rise, prompting the
need for accurate models for basic and translational research. Several model systems are …
need for accurate models for basic and translational research. Several model systems are …
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8
Abstract The RGD (Arg-Gly-Asp)-binding integrins αvβ6 and αvβ8 are clinically validated
cancer and fibrosis targets of considerable therapeutic importance. Compounds that can …
cancer and fibrosis targets of considerable therapeutic importance. Compounds that can …
Harnessing three-dimensional (3D) cell culture models for pulmonary infections: State of the art and future directions
DD Shah, NR Raghani, MR Chorawala, S Singh… - Naunyn-Schmiedeberg's …, 2023 - Springer
Pulmonary infections have been a leading etiology of morbidity and mortality worldwide.
Upper and lower respiratory tract infections have multifactorial causes, which include …
Upper and lower respiratory tract infections have multifactorial causes, which include …
Development of lung tissue models and their applications
N Petpiroon, W Netkueakul, K Sukrak, C Wang, Y Liang… - Life Sciences, 2023 - Elsevier
The lungs are important organs that play a critical role in the development of specific
diseases, as well as responding to the effects of drugs, chemicals, and environmental …
diseases, as well as responding to the effects of drugs, chemicals, and environmental …
The evolution of in vitro models of lung fibrosis: promising prospects for drug discovery
E Kolanko, A Cargnoni, A Papait… - European …, 2024 - Eur Respiratory Soc
Lung fibrosis is a complex process, with unknown underlying mechanisms, involving various
triggers, diseases and stimuli. Different cell types (epithelial cells, endothelial cells …
triggers, diseases and stimuli. Different cell types (epithelial cells, endothelial cells …
[HTML][HTML] Comprehensive review of potential drugs with anti-pulmonary fibrosis properties
J Ma, G Li, H Wang, C Mo - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Pulmonary fibrosis is a chronic and progressive lung disease characterized by the
accumulation of scar tissue in the lungs, which leads to impaired lung function and reduced …
accumulation of scar tissue in the lungs, which leads to impaired lung function and reduced …
Recent frontiers in biofabrication for respiratory tissue engineering
Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …
pathogen interactions in a tissue-like environment and offers a platform for studying lung …
Advanced lung organoids for respiratory system and pulmonary disease modeling
Amidst the recent coronavirus disease 2019 (COVID-19) pandemic, respiratory system
research has made remarkable progress, particularly focusing on infectious diseases. Lung …
research has made remarkable progress, particularly focusing on infectious diseases. Lung …
CEBPA Overexpression Enhances β-Cell Proliferation and Survival
Simple Summary The objective of this study was to define the role of the transcription factor
CEBPA on pancreatic beta cell function, replication, and survival. We have previously shown …
CEBPA on pancreatic beta cell function, replication, and survival. We have previously shown …