[HTML][HTML] Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression

E Yang, X Wang, Z Gong, M Yu, H Wu… - Signal transduction and …, 2020 - nature.com
Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …

[HTML][HTML] Obesity, diabetes, and increased cancer progression

DS Kim, PE Scherer - Diabetes & metabolism journal, 2021 - ncbi.nlm.nih.gov
Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …

American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

Cancer as a matter of fat: the crosstalk between adipose tissue and tumors

E Lengyel, L Makowski, J DiGiovanni, MG Kolonin - Trends in cancer, 2018 - cell.com
Obesity has been linked to the increased risk and aggressiveness of many types of
carcinoma. A state of chronic inflammation in adipose tissue (AT), resulting in genotoxic …

Cell-based drug delivery systems and their in vivo fate

L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

[PDF][PDF] Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer

AK Pingili, M Chaib, LM Sipe, EJ Miller, B Teng… - Cell reports, 2021 - cell.com
Immune checkpoint blockade (ICB) has improved outcomes in some cancers. A major
limitation of ICB is that most patients fail to respond, which is partly attributable to …

[HTML][HTML] Bioprinting and differentiation of adipose-derived stromal cell spheroids for a 3D breast cancer-adipose tissue model

H Horder, M Guaza Lasheras, N Grummel… - Cells, 2021 - mdpi.com
Biofabrication, including printing technologies, has emerged as a powerful approach to the
design of disease models, such as in cancer research. In breast cancer, adipose tissue has …

Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments

J O'Sullivan, J Lysaght, CL Donohoe… - Nature reviews …, 2018 - nature.com
Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …

[HTML][HTML] Mammary gland adipocytes in lactation cycle, obesity and breast cancer

G Colleluori, J Perugini, G Barbatelli, S Cinti - Reviews in Endocrine and …, 2021 - Springer
The mammary gland (MG) is an exocrine gland present in female mammals responsible for
the production and secretion of milk during the process of lactation. It is mainly composed by …