The review focuses on mechanistic evidence for the link between obesity and breast cancer.
According to the IARC study, there is sufficient evidence that obesity is closely related to a …

Breast cancer is one of the most prevalent cancers in women contributing to cancer-related
death in the advanced world. Apart from the menopausal status, the trigger for developing …

Multiple myeloma is a B-cell lineage cancer in which neoplastic plasma cells expand in the
bone marrow and pathophysiological interactions with components of microenvironment …

The tumor microenvironment (TME) has an essential role in tumor initiation and
development. Tumor cells are considered to actively create their microenvironment during …

Cancer treatment is challenged by the heterogeneous nature of cancer, where prognosis
depends on tumor type and disease stage, as well as previous treatments. Optimal patient …

The tumor microenvironment is a complex and dynamic cellular community comprising the
tumor epithelium and various tumor-supporting cells such as immune cells, fibroblasts …

Obesity is a complex metabolic condition considered a worldwide public health crisis, and a
deeper mechanistic understanding of obesity-associated diseases is urgently needed …

Bile acids (BAs) are known facilitators of nutrient absorption but recent paradigm shifts now
recognize BAs as signaling molecules regulating both innate and adaptive immunity. Bile …

Colorectal cancer (CRC) is a leading cause of cancer-related mortality in the world. Patterns
and trends in CRC incidence and mortality correlate with increasing adoption of Western …

How lifespan and body weight vary as a function of diet and genetic differences is not well
understood. Here we quantify the impact of differences in diet on lifespan in a genetically …