Abstract Background Observational and Mendelian randomization (MR) studies link obesity
and cancer, but it remains unclear whether these depend upon related metabolic …

Simple Summary Aptamers are versatile molecules for cancer treatment. They can be used
to target specific molecules, conjugated to additional nucleic acid moieties or payloads. In …

The global prevalence of cancer is increasing, necessitating new additions to traditional
treatments and diagnoses to address shortcomings such as ineffectiveness, complications …

Simple Summary In breast cancer, adipose-derived stromal cells (ASCs) and adipocytes, as
components of the mammary fat pad, come into close contact with tumor cells. To …

The tumor microenvironment (TME) is a complex network of epithelial and stromal cells,
wherein stromal components provide support to tumor cells during all stages of …

Background: Triple-negative breast cancer (TNBC) cells secretome induces a pro-
inflammatory microenvironment within the adipose tissue, which hosts both mature …

Mammalian tissue repair forms a scar that fills the injured area with a fibrotic lesion, limiting
tissue function. Adipocytes, lipid-filled cells, well-known for energy storage and endocrine …

Obesity is a well-known modifiable risk factor for breast cancer and is considered a poor
prognostic factor in pre-and post-menopausal women. While the systemic effects of obesity …

Obesity is a major public health concern at the origin of many pathologies, including
cancers. Among them, the incidence of gastro-intestinal tract cancers is significantly …

During the last ten years, many research results have been referring to a particular type of
cancer-associated fibroblasts associated with poor prognosis, invasiveness, metastasis and …