Background & aims Computed tomography (CT) scans can measure quantity and
distribution of adipose tissue, which are associated with breast cancer prognosis. As a novel …

Obesity, defined as a state of positive energy balance with a body mass index exceeding 30
kg/m2 in adults and 95th percentile in children, is an increasing global concern …

Endometrial cancer is one of the most frequently diagnosed gynecological neoplasms in
developed countries and its incidence is rising. Usually, it is diagnosed in the early stages of …

Purpose The transforming growth factor-beta (TGF-β) pathway plays a paradoxical, context-
dependent role in pancreatic ductal adenocarcinoma (PDAC): a tumor-suppressive role in …

Increasing evidence supports the critical role of active stromal adipocytes in breast cancer
development and spread. However, the mediators and the mechanisms of action are still …

Pioneering experiments performed by Harold Varmus and Mike Bishop in 1976 led to one of
the most influential discoveries in cancer research and identified the first cancer-causing …

Despite advances in therapy and achievements in translational research, pancreatic cancer
(PC) remains an invariably fatal malignancy. Risk factors that affect the incidence of PC …

Over the past decade, knowledge of cancer metabolism has expanded exponentially and
has provided several clinically relevant targets for cancer therapy. Although these current …

Lung cancer is a devastating disease with a high incidence and low survival rates, so recent
studies have focused on analyzing the risk factors that might prevent this disease from …

Simple Summary Breast cancer is the second most common cancer in women worldwide.
The risk of developing breast cancer depends on various mechanisms, such as age …