Adipose-derived mesenchymal stem cells promote the malignant phenotype of cervical cancer

R Castro-Oropeza, K Vazquez-Santillan… - Scientific Reports, 2020 - nature.com
Epidemiological studies indicate that obesity negatively affects the progression and
treatment of cervical-uterine cancer. Recent evidence shows that a subpopulation of …

Nomogram of combining CT-based body composition analyses and prognostic inflammation score: prediction of survival in advanced epithelial ovarian cancer …

X Wang, C Zhang, F Cao, C Wang, J Dong, Z Wang - Academic Radiology, 2022 - Elsevier
Purpose To investigate the value of body composition changes measured by quantitative
computer tomography (QCT) in evaluating the prognosis of advanced epithelial ovarian …

Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx

F Yang, M Duan, F Zheng, L Yu, Y Wang, G Wang… - Cancer letters, 2021 - Elsevier
Obesity is a global public health issue. Obesity-related chronic low-grade inflammation
(meta-inflammation) can lead to aberrant adipokine release and promote cardiometabolic …

DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer

AG Izquierdo, H Boughanem, A Diaz-Lagares… - Epigenetics, 2022 - Taylor & Francis
Adipose tissue dysfunction, particularly the visceral (VAT) compartment, has been proposed
to play a relevant role in colorectal cancer (CRC) development and progression. Epigenetic …

The tumor microenvironment: shaping cancer progression and treatment response

SA Desai, VP Patel, KP Bhosle, SD Nagare… - Journal of …, 2023 - Taylor & Francis
The tumor microenvironment (TME) plays a crucial role in cancer progression and treatment
response. It comprises a complex network of stromal cells, immune cells, extracellular …

The role of the adipokine resistin in the pathogenesis and progression of epithelial ovarian cancer

K Parafiniuk, W Skiba, A Pawłowska, D Suszczyk… - Biomedicines, 2022 - mdpi.com
Obesity is a civilization disease associated with an increased risk of developing
cardiovascular diseases, diabetes, and some malignancies. The results concerning the …

Emerging functions of adipokines in linking the development of obesity and cardiovascular diseases

X Su, D Peng - Molecular Biology Reports, 2020 - Springer
Increasing evidence shows that obesity is the critical factor in shaping cardio-metabolic
phenotypes. However, the pathogenic mechanisms remain incompletely clarified. According …

Visceral adipose tissue volume and CT‐attenuation as prognostic factors in patients with head and neck cancer

JW Lee, MJ Ban, JH Park, SM Lee - Head & Neck, 2019 - Wiley Online Library
Background The aim of this study was to evaluate the relationship of the characteristics of
subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) to the disease …

Context matters: Response heterogeneity to collagen-targeting approaches in desmoplastic cancers

AM Fuller, TSK Eisinger-Mathason - Cancers, 2022 - mdpi.com
Simple Summary A common feature of tumor types such as breast cancer, prostate cancer,
pancreatic cancer, and soft-tissue sarcoma is the deposition of collagen-rich tissue called …

PVT1 affects EMT and cell proliferation and migration via regulating p21 in triple-negative breast cancer cells cultured with mature adipogenic medium

L Wang, R Wang, Z Ye, Y Wang, X Li… - Acta Biochimica et …, 2018 - academic.oup.com
Excessive adiposity has long been proved to be associated with greater incidence and
mortality of breast cancer in post-menopausal women. However, the effects and underlying …