In modern society, inappropriate diets and other lifestyle habits have made obesity an
increasingly prominent health problem. Pancreatic cancer (PC), a kind of highly aggressive …

Breast cancer (BC) progression is substantially driven by cellular cross‐talk between tumor
and stromal cells within the tumor microenvironment (TME). However, lack of precise …

It is well established that the tumor microenvironment plays an important role in cancer
development and progression. The tumor microenvironment is composed of neoplastic cells …

Colorectal cancer (CRC), a multi-step malignancy showing increasing incidence in today's
societies, represents an important worldwide health issue. Exogenous factors, such as …

Adiponectin is an adipokine originally identified as dysregulated in obesity, with a key role in
insulin sensitisation and in maintaining systemic energy balance. However, adiponectin is …

During cancer progression, breast tumor cells interact with adjacent adipose tissue, which
has been shown to be engaged in cancer aggressiveness. However, the tumor-directed …

Colorectal cancer (CRC) is among the major threatening diseases worldwide, being the
third most common cancer, and a leading cause of death, with a global incidence expected …

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the human
gastrointestinal tract. In this study, we performed single‐cell RNA sequencing (RNA‐seq) on …

Gestational diabetes mellitus (GDM) is an obstetric disorder affecting approximately 10% of
pregnancies. The four high-fat, high-sucrose (HFHS) mouse model emulates GDM in lean …

Current methods to treat large soft-tissue defects mainly rely on autologous transfer of
adipocutaneous flaps, a method that is often limited by donor site availability. Engineered …