Cannabinoids and the expanded endocannabinoid system in neurological disorders
L Cristino, T Bisogno, V Di Marzo - Nature Reviews Neurology, 2020 - nature.com
Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
[HTML][HTML] Intestinal barrier function and immune homeostasis are missing links in obesity and type 2 diabetes development
S Riedel, C Pheiffer, R Johnson, J Louw… - Frontiers in …, 2022 - frontiersin.org
Noncommunicable diseases, such as type 2 diabetes (T2D), place a burden on healthcare
systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly …
systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly …
[HTML][HTML] Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat
S Castonguay-Paradis, S Lacroix, G Rochefort… - Scientific reports, 2020 - nature.com
The endocannabinoidome encompasses several fatty acid (FA)-derived mediators,
including the endocannabinoid anandamide (AEA) and 2-arachidonoyl-glycerol (2-AG) …
including the endocannabinoid anandamide (AEA) and 2-arachidonoyl-glycerol (2-AG) …
[HTML][HTML] Phytocannabinoids: Useful drugs for the treatment of obesity? Special focus on cannabidiol
P Bielawiec, E Harasim-Symbor… - Frontiers in …, 2020 - frontiersin.org
Currently, an increasing number of diseases related to insulin resistance and obesity is an
alarming problem worldwide. It is well-known that the above states can lead to the …
alarming problem worldwide. It is well-known that the above states can lead to the …
[HTML][HTML] Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono …
C Depommier, RM Vitale, FA Iannotti, C Silvestri… - Cells, 2021 - mdpi.com
Akkermansia muciniphila is considered as one of the next-generation beneficial bacteria in
the context of obesity and associated metabolic disorders. Although a first proof-of-concept …
the context of obesity and associated metabolic disorders. Although a first proof-of-concept …
[HTML][HTML] Integrative hedonic and homeostatic food intake regulation by the central nervous system: insights from neuroimaging
Food intake regulation in humans is a complex process controlled by the dynamic
interaction of homeostatic and hedonic systems. Homeostatic regulation is controlled by …
interaction of homeostatic and hedonic systems. Homeostatic regulation is controlled by …
Inflammation and nitro-oxidative stress as drivers of endocannabinoid system aberrations in mood disorders and schizophrenia
The endocannabinoid system (ECS) is composed of the endocannabinoid ligands
anandamide (AEA) and 2-arachidonoylgycerol (2-AG), their target cannabinoid receptors …
anandamide (AEA) and 2-arachidonoylgycerol (2-AG), their target cannabinoid receptors …
[HTML][HTML] Endocannabinoid system: chemical characteristics and biological activity
B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023 - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …
The endocannabinoid system, a new gatekeeper in the pharmacology of human hepatocellular carcinoma
N Ebrahimi, NP Far, SS Fakhr, F Faghihkhorasani… - Environmental …, 2023 - Elsevier
Despite numerous prevention methodologies and treatment options, hepatocellular
carcinoma (HCC) still remains as the third leading life-threatening cancer. It is thus pertinent …
carcinoma (HCC) still remains as the third leading life-threatening cancer. It is thus pertinent …
[HTML][HTML] Therapeutic potential of β-caryophyllene: a dietary cannabinoid in diabetes and associated complications
Diabetes mellitus (DM), a metabolic disorder is one of the most prevalent chronic diseases
worldwide across developed as well as developing nations. Hyperglycemia is the core …
worldwide across developed as well as developing nations. Hyperglycemia is the core …