Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …

Intravenous β‐lactam antibiotics remain a cornerstone in the management of bacterial
infections due to their broad spectrum of activity and excellent tolerability. β‐lactams are well …

Patients with cystic fibrosis (CF) are repeatedly exposed to antibiotics, especially during the
pulmonary exacerbations of the disease. However, the available therapeutic strategies are …

Pseudomonas aeruginosa biofilms cause chronic, antibiotic tolerant infections in wounds
and lungs. Numerous recent studies demonstrate that bacteria can detect human …

Pseudomonas aeruginosa remains a challenge in chronic respiratory infections in cystic
fibrosis (CF). Ceftolozane-tazobactam has not yet been evaluated against multidrug …

Cystic fibrosis (CF) is a genetic disease that causes absence or dysfunction of a protein
named transmembrane conductance regulatory protein (CFTR) that works as an anion …

Bacterial resistance to antibiotics continues to be a global public health problem. The choice
of the most effective antibiotic and the use of an adapted dose in the initial phase of the …

For those born with cystic fibrosis (CF), hyper-concentrated mucus with a dysfunctional
structure significantly impacts CF airways, providing a perfect environment for bacterial …

Cystic fibrosis is a genetic disease that results in progressive multi-organ manifestations with
predominance in the respiratory and gastrointestinal systems. The significant morbidity and …

The purpose of the work was to investigate the impact of sodium chloride (NaCl) on the
antimicrobial efficacy of ceragenins (CSAs) and antimicrobial peptides (AMPs) against …