Lung cancer statistics, 2023
Despite decades of declining mortality rates, lung cancer remains the leading cause of
cancer death in the United States. This article examines lung cancer incidence, stage at …
cancer death in the United States. This article examines lung cancer incidence, stage at …
[HTML][HTML] The RANK–RANKL–OPG System: A Multifaceted Regulator of Homeostasis, Immunity, and Cancer
D De Leon-Oliva, S Barrena-Blázquez… - Medicina, 2023 - mdpi.com
The RANK–RANKL–OPG system is a complex signaling pathway that plays a critical role in
bone metabolism, mammary epithelial cell development, immune function, and cancer …
bone metabolism, mammary epithelial cell development, immune function, and cancer …
[HTML][HTML] SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
SOD1 is known as the major cytoplasmic superoxide dismutase and an anticancer target.
However, the role of SOD1 in cancer is not fully understood. Herein we describe the …
However, the role of SOD1 in cancer is not fully understood. Herein we describe the …
Role of sex hormones in lung cancer
N Fuentes, M Silva Rodriguez… - … Biology and Medicine, 2021 - journals.sagepub.com
Lung cancer represents the world's leading cause of cancer deaths. Sex differences in the
incidence and mortality rates for various types of lung cancers have been identified, but the …
incidence and mortality rates for various types of lung cancers have been identified, but the …
[HTML][HTML] The G Protein-Coupled Estrogen Receptor (GPER): a critical therapeutic target for cancer
KA Hall, EJ Filardo - Cells, 2023 - mdpi.com
Estrogens have been implicated in the pathogenesis of various cancers, with increasing
concern regarding the overall rising incidence of disease and exposure to environmental …
concern regarding the overall rising incidence of disease and exposure to environmental …
[HTML][HTML] Estrogens, cancer and immunity
I Orzołek, J Sobieraj, J Domagała-Kulawik - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present current knowledge of sex hormones in the
process of development of malignant diseases. The impact of sex hormones on immune …
process of development of malignant diseases. The impact of sex hormones on immune …
[HTML][HTML] Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression
MJ Young, YC Chen, SA Wang, HP Chang… - Journal of biomedical …, 2022 - Springer
Background Sp1, an important transcription factor, is involved in the progression of various
cancers. Our previous studies have indicated that Sp1 levels are increased in the early …
cancers. Our previous studies have indicated that Sp1 levels are increased in the early …
[HTML][HTML] Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications
V Rodriguez-Lara, G Soca-Chafre… - Frontiers in …, 2023 - frontiersin.org
Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival
of non-small cell lung cancer (NSCLC) patients. However, differential responses have been …
of non-small cell lung cancer (NSCLC) patients. However, differential responses have been …
[HTML][HTML] An overview of lung cancer in women and the impact of estrogen in lung carcinogenesis and lung cancer treatment
V Rodriguez-Lara, MR Avila-Costa - Frontiers in medicine, 2021 - frontiersin.org
Lung cancer incidence and mortality have significantly increased in women worldwide. Lung
adenocarcinoma is the most common form of lung cancer globally. This type of lung cancer …
adenocarcinoma is the most common form of lung cancer globally. This type of lung cancer …
[HTML][HTML] Sex steroids effects on asthma: a network perspective of immune and airway cells
A multitude of evidence has suggested the differential incidence, prevalence and severity of
asthma between males and females. A compilation of recent literature recognized sex …
asthma between males and females. A compilation of recent literature recognized sex …