The neuroprotective potentiality of flavonoids on Alzheimer's disease
Alzheimer's disease (AD), due to its spread, has become a global health priority, and is
characterized by senile dementia and progressive disability. The main cause of AD and …
characterized by senile dementia and progressive disability. The main cause of AD and …
ERK/MAPK signalling in the developing brain: Perturbations and consequences
The extracellular regulated kinase/microtubule-associated protein kinase (ERK/MAPK)
signalling pathway transduces signals that cause an alteration in the ongoing metabolic …
signalling pathway transduces signals that cause an alteration in the ongoing metabolic …
The ASD Living Biology: from cell proliferation to clinical phenotype
E Courchesne, T Pramparo, VH Gazestani… - Molecular …, 2019 - nature.com
Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the
lay public because of its uncertain origins and striking and unexplained clinical …
lay public because of its uncertain origins and striking and unexplained clinical …
MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling
Rett syndrome (RTT) is an X-linked, neurodevelopmental disorder caused primarily by
mutations in the methyl-CpG-binding protein 2 (MECP2) gene, which encodes a …
mutations in the methyl-CpG-binding protein 2 (MECP2) gene, which encodes a …
MAP/ERK signaling in developing cognitive and emotional function and its effect on pathological and neurodegenerative processes
H Albert-Gascó, F Ros-Bernal… - International journal of …, 2020 - mdpi.com
The signaling pathway of the microtubule-associated protein kinase or extracellular
regulated kinase (MAPK/ERK) is a common mechanism of extracellular information …
regulated kinase (MAPK/ERK) is a common mechanism of extracellular information …
The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: A potential therapeutic target
J Sun, G Nan - International journal of molecular …, 2017 - spandidos-publications.com
Signaling pathways are critical modulators of a variety of physiological and pathological
processes, and the abnormal activation of some signaling pathways can contribute to …
processes, and the abnormal activation of some signaling pathways can contribute to …
Mechanism of quercetin therapeutic targets for Alzheimer disease and type 2 diabetes mellitus
G Zu, K Sun, L Li, X Zu, T Han, H Huang - Scientific reports, 2021 - nature.com
Quercetin has demonstrated antioxidant, anti-inflammatory, hypoglycemic, and
hypolipidemic activities, suggesting therapeutic potential against type 2 diabetes mellitus …
hypolipidemic activities, suggesting therapeutic potential against type 2 diabetes mellitus …
ERK1 and ERK2 map kinases: specific roles or functional redundancy?
R Buscà, J Pouysségur, P Lenormand - Frontiers in cell and …, 2016 - frontiersin.org
The MAP kinase signaling cascade Ras/Raf/MEK/ERK has been involved in a large variety
of cellular and physiological processes that are crucial for life. Many pathological situations …
of cellular and physiological processes that are crucial for life. Many pathological situations …
Calcium signaling in neurodegeneration
P Marambaud, U Dreses-Werringloer… - Molecular …, 2009 - Springer
Calcium is a key signaling ion involved in many different intracellular and extracellular
processes ranging from synaptic activity to cell-cell communication and adhesion. The exact …
processes ranging from synaptic activity to cell-cell communication and adhesion. The exact …
Association between plasma proteome and childhood neurodevelopmental disorders: a two-sample Mendelian randomization analysis
J Yang, X He, L Qian, B Zhao, Y Fan, F Gao, B Yan… - …, 2022 - thelancet.com
Background Childhood neurodevelopmental disorders, including autism spectrum disorder
(ASD), attention-deficit hyperactivity disorder (ADHD), and Tourette syndrome (TS) …
(ASD), attention-deficit hyperactivity disorder (ADHD), and Tourette syndrome (TS) …