[HTML][HTML] Interleukin 13 receptor alpha 2 (IL13Rα2): expression, signaling pathways and therapeutic applications in cancer
Abstract Interleukin 13 receptor alpha 2 (IL13Rα2) is increasingly recognized as a relevant
player in cancer invasion and metastasis. Despite being initially considered a decoy …
player in cancer invasion and metastasis. Despite being initially considered a decoy …
CAR based immunotherapy of solid tumours—A clinically based review of target antigens
J Maher, DM Davies - Biology, 2023 - mdpi.com
Simple Summary Cancer accounts for an increasing number of deaths year on year.
However, new immune-based therapies offer promise in the quest to address this unmet …
However, new immune-based therapies offer promise in the quest to address this unmet …
Cytokine profile in development of glioblastoma in relation to healthy individuals
P Jarmuzek, P Defort, M Kot… - International Journal of …, 2023 - mdpi.com
Cytokines play an essential role in the control of tumor cell development and multiplication.
However, the available literature provides ambiguous data on the involvement of these …
However, the available literature provides ambiguous data on the involvement of these …
Polydopamine-based loaded temozolomide nanoparticles conjugated by peptide-1 for glioblastoma chemotherapy and photothermal therapy
H Wu, T Zhang, Q Liu, M Wei, Y Li, Q Ma… - Frontiers in …, 2023 - frontiersin.org
Purpose: Nanoparticles (NPs) of the polydopamine (PDA)-based, loaded with temozolomide
(TMZ) and conjugated with Pep-1 (Peptide-1) as a feasible nano-drug delivery system were …
(TMZ) and conjugated with Pep-1 (Peptide-1) as a feasible nano-drug delivery system were …
[HTML][HTML] Type 1 and type 2 cytokine-mediated immune orchestration in the tumour microenvironment and their therapeutic potential
E Jou - Exploration of Targeted Anti-tumor Therapy, 2023 - ncbi.nlm.nih.gov
Cancer remains the second leading cause of death worldwide despite modern
breakthroughs in medicine, and novel treatments are urgently needed. The revolutionary …
breakthroughs in medicine, and novel treatments are urgently needed. The revolutionary …
Identification and characterisation of novel CAR‐T cells to target IL13Rα2 positive human glioma in vitro and in vivo
P Leland, H Degheidy, A Lea, SR Bauer… - Clinical and …, 2024 - Wiley Online Library
Background Previously, we discovered that human solid tumours, but not normal human
tissues, preferentially overexpress interleukin‐13Receptor alpha2, a high binding receptor …
tissues, preferentially overexpress interleukin‐13Receptor alpha2, a high binding receptor …
Targeting glioblastoma multiforme using a novel fusion protein comprising interleukin-13 and staphylococcal enterotoxin B in vitro
Z Gholipour, AAI Fooladi, K Parivar, R Halabian - Toxicology in Vitro, 2023 - Elsevier
Targeting cell surface receptors with immunotoxins provides a novel, unique and highly
potent treatment against cancers. A high expression of interleukin-13 (IL13) receptor α2 …
potent treatment against cancers. A high expression of interleukin-13 (IL13) receptor α2 …
Proteomic profiling and network biology of colorectal cancer liver metastasis
RA Bartolomé, JI Casal - Expert Review of Proteomics, 2023 - Taylor & Francis
Introduction Tissue-based proteomic studies of colorectal cancer (CRC) metastasis have
delivered fragmented results, with very few therapeutic targets and prognostic biomarkers …
delivered fragmented results, with very few therapeutic targets and prognostic biomarkers …
[HTML][HTML] Present status and advances in chimeric antigen receptor T cell therapy for glioblastoma
Adoptive chimeric antigen receptor (CAR) T cells designed to recognize specific tumor
antigens have shown promising results in cancer therapy. While CAR T cell therapy has …
antigens have shown promising results in cancer therapy. While CAR T cell therapy has …
Targeting and sensitization of breast cancer cells to killing with a novel interleukin-13 receptor α2-specific hybrid cytolytic peptide
R Jannoo, W Walker, V Kanamarlapudi - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is the most commonly diagnosed cancer and the second
leading cause of cancer deaths among women globally. Due to its biological heterogeneity …
leading cause of cancer deaths among women globally. Due to its biological heterogeneity …