Introduction: Sarcoidosis is a complex systemic disease with a silent, long-term evolution,
and a heterogeneous clinical presentation. The diagnostic approach is complex with no …

Human primary immunodeficiency diseases (PIDs) represent a heterogeneous group of
more than 350 disorders. They are rare diseases, but their global incidence is more relevant …

Central nervous system localizations of sarcoidosis may be refractory to conventional
treatment such as steroids and immunosuppressive drugs. Infliximab, a TNF-α antagonist …

Aims Cardiac sarcoidosis (CS) is associated with a poor prognosis. Important features of CS
include heart failure, conduction abnormalities, and ventricular arrhythmias. Ventricular …

Simple Summary Granulomatosis is commonly observed in patients receiving immune
checkpoint inhibitors (ICIs) for melanoma and other cancers. Recognizing this reaction early …

Sarcoidosis is a multisystem inflammatory disease characterized by the development of
Th1/Th17/regulatory T cells (Tregs)‑related non‑caseating granulomas. Phosphoinositide‑3 …

Sarcoidosis is a chronic granulomatous disease that can virtually affect any organ. Its
etiology is unknown, although it has been proposed that environmental or biological agents …

Migraine and sarcoidosis are two distinct medical conditions that may have some common
biological and clinical pathways. Sarcoidosis is a chronic granulomatous disease …

Evidence points at microenvironment and cell functional features rather than cell
polarization or differentiation as determinants of pathogenesis. In terms of therapeutic …

Sarcoidosis is a systemic granulomatous disorder of unknown etiology, with a predilection
for the respiratory system, involved in more than 90% of cases, with considerable variability …