[HTML][HTML] Advances and challenges in stem cell culture

C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …

Modulating the stem cell niche for tissue regeneration

SW Lane, DA Williams, FM Watt - Nature biotechnology, 2014 - nature.com
The field of regenerative medicine holds considerable promise for treating diseases that are
currently intractable. Although many researchers are adopting the strategy of cell …

[PDF][PDF] Expanded umbilical cord mesenchymal stem cells (UC-MSCs) as a therapeutic strategy in managing critically ill COVID-19 patients: the case for compassionate …

S Atluri, L Manchikanti, JA Hirsch - Pain physician, 2020 - sah.org.ar
2. Institute appropriate safeguards to avoid negative consequences from unscrupulous
actors. 3. With proper informed consent from patients or proxy when necessary, and subject …

Stem cell-based bone and dental regeneration: a view of microenvironmental modulation

C Zheng, J Chen, S Liu, Y Jin - International Journal of Oral Science, 2019 - nature.com
In modern medicine, bone and dental loss and defects are common and widespread
morbidities, for which regenerative therapy has shown great promise. Mesenchymal stem …

Mobile microrobots for active therapeutic delivery

P Erkoc, IC Yasa, H Ceylan, O Yasa… - Advanced …, 2019 - Wiley Online Library
Recent advances in the versatility and sophistication of design, fabrication, and control
methods of mobile microrobots could have a transforming impact on future healthcare …

Challenges and strategies for improving the regenerative effects of mesenchymal stromal cell-based therapies

S Baldari, G Di Rocco, M Piccoli, M Pozzobon… - International journal of …, 2017 - mdpi.com
Cell-based therapies have the potential to revolutionize current treatments for diseases with
high prevalence and related economic and social burden. Unfortunately, clinical trials have …

Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics

KG Chen, BS Mallon, RDG McKay, PG Robey - Cell stem cell, 2014 - cell.com
Human pluripotent stem cells (hPSCs) provide powerful resources for application in
regenerative medicine and pharmaceutical development. In the past decade, various …

The translation of cell-based therapies: clinical landscape and manufacturing challenges

TRJ Heathman, AW Nienow, MJ McCall… - Regenerative …, 2015 - Taylor & Francis
Cell-based therapies have the potential to make a large contribution toward currently unmet
patient need and thus effective manufacture of these products is essential. Many challenges …

Ethical issues in stem cell research and therapy

NMP King, J Perrin - Stem Cell Research & Therapy, 2014 - Springer
Rapid progress in biotechnology has introduced a host of pressing ethical and policy issues
pertaining to stem cell research. In this review, we provide an overview of the most …

Concise review: a comprehensive analysis of reported adverse events in patients receiving unproven stem cell-based interventions

G Bauer, M Elsallab… - Stem cells translational …, 2018 - academic.oup.com
The promise of stem cell (SC) therapies to restore functions of damaged tissues and organs
brings enormous hope to patients, their families, loved ones, and caregivers. However, limits …