Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Decreased dendritic spine density in the cortex is a hallmark of several neuropsychiatric
diseases, and the ability to promote cortical neuron growth has been hypothesized to …

Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

Basolateral amygdala (BLA) principal cells are capable of driving and antagonizing
behaviors of opposing valence. BLA neurons project to the central amygdala (CeA), which …

Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Pathological fear and anxiety are highly debilitating and, despite considerable advances in
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …

Serotonin 5-HT2A receptors (5-HT2ARs) are widely distributed in the central nervous
system, especially in brain region essential for learning and cognition. In addition to …

Abstract Serotonergic hallucinogens, such as (+)-lysergic acid diethylamide, psilocybin, and
mescaline, are somewhat enigmatic substances. Although these drugs are derived from …