Phytochemicals and regulation of NF-kB in inflammatory bowel diseases: an overview of in vitro and in vivo effects

LF Laurindo, ARO Santos, ACA Carvalho, MD Bechara… - Metabolites, 2023 - mdpi.com
Inflammatory bowel diseases (IBD) are chronic relapsing idiopathic inflammatory conditions
affecting the gastrointestinal tract. They are mainly represented by two forms, ulcerative …

Treatment effects of natural products on inflammatory bowel disease in vivo and their mechanisms: Based on animal experiments

Y Zhou, D Wang, W Yan - Nutrients, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory disease of the
intestine that can be classified as ulcerative colitis (UC) and Crohn's disease (CD) …

Natural compounds: Wnt pathway inhibitors with therapeutic potential in lung cancer

X Shen, C Gao, H Li, C Liu, L Wang, Y Li… - Frontiers in …, 2023 - frontiersin.org
The Wnt/β-catenin pathway is abnormally activated in most lung cancer tissues and
considered to be an accelerator of carcinogenesis and lung cancer progression, which is …

Purification and characterization of a glycoprotein from Sipunculus nudus and its immune-enhancing activity to RAW 264.7 macrophages

X Lu, Y Dai, S Yang, T Fu, Y He, F Zeng, T Chen… - Food Research …, 2023 - Elsevier
Sipunculus nudus, an edible marine invertebrate, has long been used as traditional Chinese
medicine in folk remedies. In order to assess the immunoregulatory activity of glycoproteins …

Daurisoline attenuates H2O2-induced chondrocyte autophagy by activating the PI3K/Akt/mTOR signaling pathway

Y Zhang, W Liu, Z Liu, Y Liu - Journal of Orthopaedic Surgery and …, 2023 - Springer
Background Osteoarthritis (OA) is a chronic degenerative joint disease characterized by
cartilage degeneration and intra-articular inflammation. Daurisoline (DAS) is an isoquinoline …

Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity

HT Yin, JH Yang, Q Li, M Li, QQ Zhao, ZP Wen - Biochemical …, 2024 - Elsevier
Glioma is one of the most common primary malignant tumors of the central nervous system.
Temozolomide (TMZ) is the only effective chemotherapeutic agent, but it easily develops …

Research progress on pharmacological effects and mechanisms of cepharanthine and its derivatives

L Shi, S Wang, S Zhang, J Wang, Y Chen, Y Li… - Naunyn-Schmiedeberg's …, 2023 - Springer
Cepharanthine (CEP) is a bisbenzylisoquinoline alkaloid compound found in plants of the
Stephania genus, which has biological functions such as regulating autophagy, inhibiting …

Schisandrin A Suppresses Inflammation in DSS-induced IBD Mice and H2O2-induced MODE-K Cells through Wnt/β-Catenin Signaling

H Xu, X Chen, X Li, D Dou, Z Xu - Pharmacognosy …, 2023 - journals.sagepub.com
Background Schisandrin A (SchA) has multiple pharmacological features, and inflammatory
bowel disease (IBD) represents a common digestive system disease mainly characterized …

[PDF][PDF] The Role of MMP-9 in Regulating Degradation of the Splenic Microvascular Basement Membrane Induced by High Altitude Hypoxia.

Y Ma, LM Zhu, WL Liu, YJ Yin, XC Peng… - International Journal of …, 2023 - intjmorphol.com
To investigate changes of MMP-9 in the rat spleen and hypoxia-induced microvascular
basement membrane under high altitude hypoxia. Thirty male specific pathogen-free …

Rol de la MMP-9 en la Regulación de la Degradación de la Membrana Basal Microvascular Esplénica Inducida por Hipoxia de Altura

Y Ma, LM Zhu, WL Liu, YJ Yin, XC Peng… - International Journal of …, 2023 - SciELO Chile
To investigate changes of MMP-9 in the rat spleen and hypoxia-induced microvascular
basement membrane under high altitude hypoxia. Thirty male specific pathogen-free …