The immunosuppressive effect of the endocannabinoid system on the inflammatory phenotypes of macrophages and mesenchymal stromal cells: a comparative study

T Ruhl, C Corsten, JP Beier, BS Kim - Pharmacological Reports, 2021 - Springer
Background The inflammatory sequence is the first phase of wound healing. Macrophages
(MPhs) and mesenchymal stromal cells (MSCs) respond to an inflammatory …

Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals

S Chen, C Chu, C Wang, Y Yang, Z Xu, Y Qu, Y Man - Biomaterials, 2024 - Elsevier
Extracellular matrix (ECM) scaffold membranes have exhibited promising potential to better
the outcomes of wound healing by creating a regenerative microenvironment around …

Platelets interact with CD169+ macrophages and cDC1 and enhance liposome-induced CD8+ T cell responses

J Grabowska, V Léopold, K Olesek… - Frontiers in …, 2023 - frontiersin.org
Historically platelets are mostly known for their crucial contribution to hemostasis, but there
is growing understanding of their role in inflammation and immunity. The immunomodulatory …

Platelet toll-like-receptor-2 and-4 mediate different immune-related responses to bacterial ligands

M Niklaus, P Klingler, K Weber, A Koessler, S Kuhn… - TH Open, 2022 - thieme-connect.com
Background Like immune cells, platelets express toll-like receptors (TLRs) on their surface
membrane. TLR2 and TLR4 are able to recognize bacterial antigens and have the potential …

Quantitative and qualitative platelet derangements in cardiac surgery and extracorporeal life support

E Squiccimarro, F Jiritano, GF Serraino… - Journal of Clinical …, 2021 - mdpi.com
Thrombocytopenia and impaired platelet function are known as intrinsic drawbacks of
cardiac surgery and extracorporeal life supports (ECLS). A number of different factors …

Platelets in Kawasaki disease: mediators of vascular inflammation

M Noval Rivas, B Kocatürk, BS Franklin… - Nature Reviews …, 2024 - nature.com
Kawasaki disease, a systemic vasculitis that affects young children and can result in
coronary artery aneurysms, is the leading cause of acquired heart disease among children …

Junin virus triggers macrophage activation and modulates polarization according to viral strain pathogenicity

MF Ferrer, P Thomas, AO López Ortiz… - Frontiers in …, 2019 - frontiersin.org
The New World arenavirus Junin (JUNV) is the etiological agent of Argentine hemorrhagic
fever (AHF). Previous studies of human macrophage infection by the Old-World …

Early platelet dysfunction in patients receiving extracorporeal membrane oxygenation is associated with mortality

PM Siegel, J Chalupsky, CB Olivier, I Bojti… - Journal of Thrombosis …, 2022 - Springer
Extracorporeal membrane oxygenation (ECMO) is used for patients with cardiopulmonary
failure and is associated with severe bleeding and poor outcome. Platelet dysfunction may …

Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization

F Li, Z Rong, R Zhang, S Niu, X Di, L Ni, C Liu - Iscience, 2022 - cell.com
Vascular restenosis is the main factor affecting the prognosis of angioplasty in
cardiovascular diseases, and inflammation is a central link in the progression of restenosis …

Platelets modulate CD4+ T‐cell function in COVID‐19 through a PD‐L1 dependent mechanism

A Paletta, F Di Diego Garcia, A Varese… - British journal of …, 2022 - Wiley Online Library
Severe COVID‐19 is associated with a systemic inflammatory response and progressive
CD4+ T‐cell lymphopenia and dysfunction. We evaluated whether platelets might contribute …