Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 may be associated with long-
term adverse effects such as cytopenia and immune deficiency. In order to characterize …

The translation of natural killer (NK) cells to the treatment of malignant disease has made
significant progress in the last few decades. With a variety of available sources and …

Opinion statement Natural killer (NK) cells have played a critical—if largely unrecognized or
ignored—role in the treatment of B cell non-Hodgkin lymphoma (NHL) since the introduction …

Patients with acute myeloid leukaemia (AML) have a five‐year survival rate of 28· 7%.
Natural killer (NK)‐cell have anti‐leukaemic activity. Here, we report on a series of 13 …

After allogeneic stem cell transplantation (alloSCT), several immune checkpoints play an
important role in the antileukemic immune response in the bone marrow (BM) …

As an important treatment for acute myeloid leukemia, allogeneic hematopoietic stem cell
transplantation (allo-HSCT) plays an important role in reducing relapse and improving long …

Natural killer (NK) cells are an important defender against infections and tumors. Their
function is regulated by the balance of inhibitory and activating receptors. Among all …

Mature immunocompetent cells from the stem cell graft as well as early robust immune
reconstitution are essential for the graft-vs.-tumor (GVT) effect to eliminate residual …

High relapse rate of acute myeloid leukemia (AML) is still a crucial problem despite
considerable advances in anti-cancer therapies. One crucial cause of relapse is the …

In the context of allogeneic transplant platforms, human leukocyte antigen (HLA)-
haploidentical hematopoietic stem cell transplantation (haplo-HSCT) represents one of the …