[HTML][HTML] Antibacterial gas therapy: strategies, advances, and prospects
TY Wang, XY Zhu, FG Wu - Bioactive Materials, 2023 - Elsevier
One of the challenges posed by current antibacterial therapy is that the expanded and
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation
SW Ryter, AMK Choi - Translational Research, 2016 - Elsevier
The heme oxygenase-1 (HO-1) enzyme system remains an attractive therapeutic target for
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …
Carbon monoxide–physiology, detection and controlled release
SH Heinemann, T Hoshi, M Westerhausen… - Chemical …, 2014 - pubs.rsc.org
Carbon monoxide (CO) is increasingly recognized as a cell-signalling molecule akin to nitric
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …
Carbon‐monoxide‐releasing molecules for the delivery of therapeutic CO in vivo
S García‐Gallego… - Angewandte Chemie …, 2014 - Wiley Online Library
The development of carbon‐monoxide‐releasing molecules (CORMs) as pharmaceutical
agents represents an attractive and safer alternative to administration of gaseous CO. Most …
agents represents an attractive and safer alternative to administration of gaseous CO. Most …
Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
Red light‐triggered intracellular carbon monoxide release enables selective eradication of MRSA infection
J Cheng, G Gan, Z Shen, L Gao, G Zhang… - Angewandte …, 2021 - Wiley Online Library
Carbon monoxide (CO) is an important gaseous signaling molecule. The use of CO‐
releasing molecules such as metal carbonyls enables the elucidation of the pleiotropic …
releasing molecules such as metal carbonyls enables the elucidation of the pleiotropic …
Ruthenium complexes in the fight against pathogenic microorganisms. An extensive review
AC Munteanu, V Uivarosi - Pharmaceutics, 2021 - mdpi.com
The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …
populations of microorganisms. Clearly, one can see the need to develop new, more …
[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3
HM Southam, TW Smith, RL Lyon, C Liao, CR Trevitt… - Redox biology, 2018 - Elsevier
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
The Triple Crown: NO, CO, and H2S in cancer cell biology
PP Oza, K Kashfi - Pharmacology & Therapeutics, 2023 - Elsevier
Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) are three
endogenously produced gases with important functions in the vasculature, immune defense …
endogenously produced gases with important functions in the vasculature, immune defense …
'Carbon-monoxide-releasing molecule-2 (CORM-2)'is a misnomer: ruthenium toxicity, not CO release, accounts for its antimicrobial effects
HM Southam, MP Williamson, JA Chapman, RL Lyon… - Antioxidants, 2021 - mdpi.com
Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …