Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy
worldwide with a poor prognosis and high mortality. More than two-thirds of HNSCC patients …

Autophagy is an important mechanism for tumor escape, allowing tumor cells to recover from
the damage induced by chemotherapy, radiation therapy, and immunotherapy and …

Simple Summary Since the micro-environment of colonic tumors, including their immune
structure would affect the response to treatments, we study the response of five groups of …

Aim The change in the levels of peripheral inflammatory markers together with EGFR in
relation to 5-fluorouracil (5-FU) therapy was evaluated for their prognostic significance in …

Intracellular delivery of DNA is considered a challenge in biological research and treatment
of diseases. The previously reported transfection rate by commercially available transfection …

Aim: Considering the central role of dendritic cells (DCs) on the development of an antitumor
immune response, in this study we used a murine model to evaluate how DC transfection …

Dendritic cells (DCs) play a leading role in generating immune responses against infectious
and malignant diseases, in addition to being able to regulate autoimmune and allergic …

As one of the major causes of cancer-related death, gastrointestinal cancer seriously
impacts the quality of human life. Moreover, in the majority of patients, the disease is in an …

We have previously observed that treatment of both human and murine dendritic cells (DCs)
treated with ultra-low doses of the antitumor agent 5-fluorouracil (5-FU) improves their …

Since conventional chemo-and radiotherapy and surgery are not completely satisfactory to
fight cancer, active and passive immunotherapeutic approaches have figured as effective …