Elective neck dissection vs observation in early-stage squamous cell carcinoma of the oral tongue with no clinically apparent lymph node metastasis in the neck: a …

S Abu-Ghanem, M Yehuda, NN Carmel… - … –Head & Neck …, 2016 - jamanetwork.com
Importance The elective management of no clinical or radiologic evidence of lymph node
metastasis in the neck (cN0) in early stage T1-T2 oral tongue squamous cell carcinoma …

Prognostic evaluation of oral tongue cancer: means, markers and perspectives (II)

IO Bello, Y Soini, T Salo - Oral oncology, 2010 - Elsevier
Squamous cell carcinoma of the oral (mobile) tongue (OTSCC) is increasingly regarded as a
biologically different entity compared to cancer affecting other oral sites. It is more …

Comparison of supervised machine learning classification techniques in prediction of locoregional recurrences in early oral tongue cancer

RO Alabi, M Elmusrati, I Sawazaki‐Calone… - International journal of …, 2020 - Elsevier
Background The proper estimate of the risk of recurrences in early-stage oral tongue
squamous cell carcinoma (OTSCC) is mandatory for individual treatment-decision making …

For early-stage oral tongue cancer, depth of invasion and worst pattern of invasion are the strongest pathological predictors for locoregional recurrence and mortality

A Almangush, IO Bello, RD Coletta, AA Mäkitie… - Virchows Archiv, 2015 - Springer
Despite early diagnosis and treatment, almost 20% of patients with early-stage (cT1-cT2N0)
oral tongue squamous cell carcinoma (OTSCC) still die of their disease. The prognosis of …

Machine learning application for prediction of locoregional recurrences in early oral tongue cancer: a Web-based prognostic tool

RO Alabi, M Elmusrati, I Sawazaki-Calone… - Virchows Archiv, 2019 - Springer
Estimation of risk of recurrence in early-stage oral tongue squamous cell carcinoma
(OTSCC) remains a challenge in the field of head and neck oncology. We examined the use …

A simple novel prognostic model for early stage oral tongue cancer

A Almangush, RD Coletta, IO Bello, C Bitu… - International journal of …, 2015 - Elsevier
The prognostication of patient outcome is one of the greatest challenges in the management
of early stage oral tongue squamous cell carcinoma (OTSCC). This study introduces a …

Salivary biomarkers for detection of oral squamous cell carcinoma: current state and recent advances

M Yakob, L Fuentes, MB Wang, E Abemayor… - Current oral health …, 2014 - Springer
Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral
cavity. Detection of OSCC is currently based on a thorough clinical oral examination …

The immune phenotype of tongue squamous cell carcinoma predicts early relapse and poor prognosis

G Troiano, C Rubini, L Togni, VCA Caponio… - Cancer …, 2020 - Wiley Online Library
Background In patients with squamous cell carcinoma of the oral tongue (OTSCC), current
tumor node metastasis staging system fails to identify at‐risk patients associated with early …

Clinical outcomes for T1-2N0-1 oral tongue cancer patients underwent surgery with and without postoperative radiotherapy

SJ Shim, J Cha, WS Koom, GE Kim, CG Lee… - Radiation …, 2010 - Springer
Background The aim of this study was to assess the results of curative surgery with and
without radiotherapy in patients with T 1-2 N 0-1 oral tongue squamous cell carcinoma …

The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas

M Agostini, LY Almeida, DC Bastos, RM Ortega… - Molecular cancer …, 2014 - AACR
Fatty acid synthase (FASN) is the biosynthetic enzyme responsible for the endogenous
synthesis of fatty acids. It is downregulated in most normal cells, except in lipogenic tissues …