Cancer is one of the leading causes of death in patients worldwide, where invasion and
metastasis are directly responsible for this statement. Although cancer therapy has …

The transcription factor NRF2 is constitutively active in glioblastoma, a highly aggressive
brain tumor subtype with poor prognosis. Temozolomide (TMZ) is the primary …

Inflammation is associated with a series of diseases like cancer, cardiovascular disease and
infection, and phosphorylation/dephosphorylation modification of proteins are important in …

Background The extension of average life expectancy and the aggravation of population
aging have become the inevitable trend of human development. In an aging society, various …

Background Names of natural products (NP) are usually given depending on the species of
origin, be it a plant, a marine organism or a microbial species. In some cases, names have …

The COVID-19 pandemic caused by SARS-CoV-2 continues to pose a threat to public
health, and extensive research by scientists worldwide has also prompted the development …

The fibrillogenesis of amyloid β-protein (Aβ) gradually accumulates to form neurotoxic Aβ
aggregates in the human brain, which is the direct cause of Alzheimer's disease (AD) related …

Background Cluster heatmaps are widely used in biology and other fields to uncover
clustering patterns in data matrices. Most cluster heatmap packages provide utility functions …

Brazilin is the main compound in Caesalpinia sappan and Haematoxylum braziletto, which
is identified as a homoisoflavonoid based on its molecular structure. These plants are …

Rearranged homoisoflavonoids constitute a unique group of natural products, renowned for
their structural diversity and complexity. These compounds, derived from modifications in the …