[HTML][HTML] Drug-induced oxidative stress in cancer treatments: angel or devil?
H Jiang, J Zuo, B Li, R Chen, K Luo, X Xiang, S Lu… - Redox Biology, 2023 - Elsevier
Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …
most significant biological events in cancer progression. Cancer cells generally represent a …
[HTML][HTML] EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions
One of the malignant tumors in women that has involved both developed and developing
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …
Cinnamon cassia oil chitosan nanoparticles: Physicochemical properties and anti-breast cancer activity
X Xu, Q Li, W Dong, G Zhao, Y Lu, X Huang… - International Journal of …, 2023 - Elsevier
The aim of this study was to prepare Cinnamomum cassia essential oil (CEO) impregnated
chitosan nanoparticles (CS-CEO) and assess its pharmacological activity against breast …
chitosan nanoparticles (CS-CEO) and assess its pharmacological activity against breast …
MnTnHex-2-PyP5+ Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells
The manganese (III) porphyrin MnTnHex-2-PyP5+ (MnTnHex) is a potent superoxide
dismutase mimic and modulator of redox-based transcriptional activity that has been studied …
dismutase mimic and modulator of redox-based transcriptional activity that has been studied …
Gallic acid suppresses the progression of triple-negative breast cancer HCC1806 cells via modulating PI3K/AKT/EGFR and MAPK signaling pathways
S Lin, HZ Qin, ZY Li, H Zhu, L Long… - Frontiers in Pharmacology, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a severe threat to women's health because of its
aggressive nature, early age of onset, and high recurrence rate. Therefore, in this study, we …
aggressive nature, early age of onset, and high recurrence rate. Therefore, in this study, we …
Single-Cell Profiling Reveals Immune-Based Mechanisms Underlying Tumor Radiosensitization by a Novel Mn Porphyrin Clinical Candidate, MnTnBuOE-2-PyP5+ …
SU Noh, J Lim, SW Shin, Y Kim, WY Park… - Antioxidants, 2024 - mdpi.com
Manganese porphyrins reportedly exhibit synergic effects when combined with irradiation.
However, an in-depth understanding of intratumoral heterogeneity and immune pathways …
However, an in-depth understanding of intratumoral heterogeneity and immune pathways …
Cellular localization of selected porphyrins and their effect on the In Vitro motility of human colon tumors and normal cells
MP Frant, M Trytek, K Deryło, M Kutyła, R Paduch - Molecules, 2023 - mdpi.com
Standard therapies for colorectal cancer cannot eliminate or sufficiently reduce the
metastasis process. Photodynamic therapy (PDT) may be an alternative to minimizing this …
metastasis process. Photodynamic therapy (PDT) may be an alternative to minimizing this …
[HTML][HTML] Anticancer Effects of radiation dose and dose fractionation on X-ray-induced photodynamic therapy
R Li, P Gao, M Dai, F Xu, Z Tian, T Liu, J Zhou… - Journal of Radiation …, 2024 - Elsevier
Preclinical research has established X-ray-induced photodynamic therapy (X-PDT) as a
highly acknowledged antitumor therapy. X-rays play an important role in the X-PDT process …
highly acknowledged antitumor therapy. X-rays play an important role in the X-PDT process …
Emerging Trends in Metal‐based Anticancer Agents: Drug Design to Clinical Trials and their Mechanism of Action
A Temesgen, HC Ananda Murthy, AZ Enyew… - …, 2023 - Wiley Online Library
Metal‐based therapeutic strategies have been effectively used to treat a number of diseases
since the ancient period. However, the issue that emerged at this time was the indistinct …
since the ancient period. However, the issue that emerged at this time was the indistinct …
[HTML][HTML] 盐酸小檗碱通过激活EMT 促进小鼠乳腺癌肺转移的作用机制
袁志莹, 马恩, 沃达, 彭军, 朱伟东, 任丹妮 - 肿瘤防治研究, 2023 - html.rhhz.net
目的从上皮-间质转化(EMT) 途径探讨盐酸小檗碱(BBR) 对小鼠乳腺癌肺转移的作用及机制.
方法CCK-8 法检测BBR 对乳腺癌4T1 细胞增殖的影响; Transwell 实验检测BBR 对4T1 …
方法CCK-8 法检测BBR 对乳腺癌4T1 细胞增殖的影响; Transwell 实验检测BBR 对4T1 …