Chlorpyrifos induces endoplasmic reticulum stress in JEG-3 cells

L Reyna, J Flores-Martín, ME Ridano… - Toxicology in Vitro, 2017 - Elsevier
Chlorpyrifos (CPF) is an organophosphorous pesticide widely used in agricultural, industrial,
and household applications. We have previously shown that JEG-3 cells are able to …

[HTML][HTML] The cellular basis of fetal endoplasmic reticulum stress and oxidative stress in drug-induced neurodevelopmental deficits

SYA Tsai, RM Bendriem, CTD Lee - Neurobiology of Stress, 2019 - Elsevier
Prenatal substance exposure is a growing public health concern worldwide. Although the
opioid crisis remains one of the most prevalent addiction problems in our society, abuse of …

Neurological Effects of Combining Low Toxic Dose of Tramadol and Nicotine: An Animal Model Evidence of Endoplasmic Reticulum Stress

D Ghorab, EM Abu-El-Rub… - BioMed Research …, 2023 - Wiley Online Library
Tramadol abuse is a common problem in the Middle East in conjunction with smoking. The
current study applied immunohistochemistry, western blot, real‐time PCR, and ELISA to test …

The effect of nicotine and dextrose on endoplasmic reticulum stress in human coronary artery endothelial cells

K Gonzales, V Feng, P Bikkina, MA Landicho… - Toxicology …, 2021 - academic.oup.com
Cigarette smoking is one of the major causes of coronary artery disease (CAD) as is
diabetes. However, nicotine has been generally regarded as safe and is used in smoking …

Neonatal nicotine exposure affects adult rat hepatic pathways involved in endoplasmic reticulum stress and macroautophagy in a sex-dependent manner

LL Souza, CL Rossetti, TC Peixoto… - … Origins of Health and …, 2023 - cambridge.org
Nonalcoholic fatty liver disease (NAFLD) involves changes in hepatic pathways, as
lipogenesis, oxidative stress, endoplasmic reticulum (ER) stress, and macroautophagy …

The unfolded protein response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsia

S Thomson, KA Waters, A Hennessy… - Reproductive …, 2021 - Elsevier
Maternal cigarette smoking (CS) and pre-eclampsia (PE) alter placental function and
expression of important proteins which maintain homeostasis. Two interlinked pathways of …

Promotion of the unfolding protein response in orexin/dynorphin neurons in sudden infant death syndrome (SIDS): elevated pPERK and ATF4 expression

NJ Hunt, KA Waters, R Machaalani - Molecular Neurobiology, 2017 - Springer
We previously demonstrated that sudden infant death syndrome (SIDS) infants have
decreased orexin immunoreactivity within the hypothalamus and pons compared to non …

Nicotine exposure disrupts placental development via the Notch signaling pathway

QR Sun, DY Wu, JJ Zhang, LH Wu, X Zhang… - …, 2023 - rep.bioscientifica.com
In brief Normal gene expression during early embryonic development and in the placenta is
crucial for a successful pregnancy. Nicotine can disrupt normal gene expression during …

RUNX1 gene expression changes in the placentas of women smokers

LG Bermudez, I Madariaga… - Experimental and …, 2021 - spandidos-publications.com
The placenta can be affected by environmental factors, such as exposure to cigarette smoke.
This exposure in the fetal context is considered a risk factor for the development of short …

[HTML][HTML] The effect of ethanol and nicotine on ER stress in human placental villous explants

M Huovinen, F Ietta, JK Repo, L Paulesu… - Current Research in …, 2022 - Elsevier
Pregnant mothers continue smoking and drinking during pregnancy. To clarify the
mechanisms of nicotine and ethanol toxicity during development, we have examined their …