Calcimimetic and calcilytic drugs: feats, flops, and futures

EF Nemeth, WG Goodman - Calcified Tissue International, 2016 - Springer
The actions of extracellular Ca 2+ in regulating parathyroid gland and kidney functions are
mediated by the extracellular calcium receptor (CaR), a G protein-coupled receptor. The …

Environmental Endocrinology: Parabens Hazardous Effects on Hypothalamic–Pituitary–Thyroid Axis

DBC Azeredo, D de Sousa Anselmo, P Soares… - International journal of …, 2023 - mdpi.com
Parabens are classified as endocrine-disrupting chemicals (EDCs) capable of interfering
with the normal functioning of the thyroid, affecting the proper regulation of the biosynthesis …

L-Amino Acids Promote Calcitonin Release via a Calcium-Sensing Receptor: Gq/11-Mediated Pathway in Human C-Cells

H Mun, KM Leach, AD Conigrave - Endocrinology, 2019 - academic.oup.com
Human calcitonin release is promoted by elevated extracellular Ca2+ (Ca2+ o)
concentration acting, at least in part, via the calcium-sensing receptor (CaSR). The CaSR is …

[HTML][HTML] Age-related association of calcitonin with parameters of anthropometry, bone and calcium metabolism during childhood

J Sonntag, M Vogel, M Geserick, F Eckelt… - Hormone Research in …, 2021 - karger.com
Introduction: The thyroid parafollicular hormone calcitonin (CT) shows particularly high
blood levels in early childhood, a period of high bone turnover, which decrease with …

Rate‐dependency of calcitonin secretion in response to increased plasma Ca2+

W Wang, E Lewin, K Olgaard - European journal of clinical …, 2002 - Wiley Online Library
Background Calcitonin (CT) is a polypeptide hormone secreted from C‐cells of the thyroid
gland in response to hypercalcemia. The physiological contribution of CT to calcium …

[图书][B] The physiological basis of metabolic bone disease

BEC Nordin, HA Morris, P Anderson - 2014 - books.google.com
Research into metabolic bone disease has made remarkable progress over the last 20
years, with the identification of numerous new molecules and pathways regulating bone …

Environmental Endocrinology: Parabens hazardous effects on HPT axis

DBC Azeredo, D de Sousa Anselmo, P Soares… - 2023 - preprints.org
Parabens are classified as endocrine disrupting compounds (EDCs), capable of interfering
with the normal functioning of the thyroid, affecting the proper regulation of the biosynthesis …

Thyroid C cells of middle-aged rats treated with estradiol or calcium

M Sekulim, M Lovren, V Miloševim, M Mimim… - Histochemistry and cell …, 1998 - Springer
The structure and function of C cells of middle-aged female rats (14-months old) treated with
estradiol dipropionate (EDP), calcium (Ca) or a combination of EDP+ Ca were studied. A …

[HTML][HTML] Functional expression of sperm angiotensin II type I receptor in Xenopus oocyte: modulation of a sperm Ca2+-activated K+ channel

SC So, WL Wu, J Grima, PS Leung, YW Chung… - … et Biophysica Acta (BBA …, 1998 - Elsevier
In addition to Ca2+ and K+ fluxes, angiotensin II (Ang II) has been shown to influence sperm
motility. The present study investigated the involvement of angiotensin II type 1 receptor …

Comparative study of changes in activity of calcitonin-producing cells in the thyroid and lungs during hypercalcemia

B Sawicki, I Kasacka, C Nowosielski - Acta histochemica, 2006 - Elsevier
The conflicting results of previous evaluations of the influence of hypercalcemia on thyroid C-
cells and the absence of reports on its influence on calcitonin (CT)-producing cells of the …