ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: Design, synthesis, anti-cancer activity, and drug-resistance reversal …
F Ma, Y Li, M Cai, W Yang, Z Wu, J Dong… - European Journal of …, 2024 - Elsevier
Activating apoptosis has long been viewed as an anti-cancer process, but recently
increasing evidence has accumulated that induction of ferroptosis has emerged as a …
increasing evidence has accumulated that induction of ferroptosis has emerged as a …
Novel NF-κB Inhibitor-Conjugated Pt (IV) Prodrug to Enable Cancer Therapy through ROS/ER Stress and Mitochondrial Dysfunction and Overcome Multidrug …
M Wang, G Li, G Jiang, J Cai, Z Liu… - Journal of Medicinal …, 2024 - ACS Publications
Although cisplatin has been widely used for clinical purposes, its application is limited due to
its obvious side effects. To mitigate the defects of cisplatin, here, six “multitarget prodrugs” …
its obvious side effects. To mitigate the defects of cisplatin, here, six “multitarget prodrugs” …
Glycyrrhetinic Acid as a Hepatocyte Targeting Ligand-Functionalized Platinum (IV) Complexes for Hepatocellular Carcinoma Therapy and Overcoming Multidrug …
X Huang, G Li, H Li, W Zhong, G Jiang… - Journal of Medicinal …, 2024 - ACS Publications
Promising targeted therapy options to overcome drug resistance and side effects caused by
platinum (II) drugs for treatment in hepatocellular carcinoma are urgently needed. Herein, six …
platinum (II) drugs for treatment in hepatocellular carcinoma are urgently needed. Herein, six …
Discovery of the Next-Generation Platinum-Based Anticancer Agents for Combating Oxaliplatin-Induced Drug Resistance
Z Sun, J Han, J Xu, W Song, Y Cui, Y Liu… - Journal of Medicinal …, 2024 - ACS Publications
Oxaliplatin-based chemotherapy has proven to be one of the most effective treatments for
advanced or metastatic colorectal cancer. However, increasing clinical resistance to …
advanced or metastatic colorectal cancer. However, increasing clinical resistance to …
Cell death mechanisms in human cancers: Biological profile and therapeutic perspective
M Ashrafizadeh - Journal of Cancer Biomoleculars and …, 2024 - eternopublisher.com
A prominent cause of death among patients is cancer that can result from somatic mutations
and exposure to environmental factors, among others. The treatment of cancer has been …
and exposure to environmental factors, among others. The treatment of cancer has been …