Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …

The coronavirus disease (COVID-19) breakout had an unimaginable worldwide effect in the
21st century, claiming millions of lives and putting a huge burden on the global economy …

The insertion of precise genetic modifications by genome editing tools such as CRISPR-
Cas9 is limited by the relatively low efficiency of homology-directed repair (HDR) compared …

Viral infections are responsible for several chronic and acute diseases in both humans and
animals. Despite the incredible progress in human medicine, several viral diseases, such as …

Viruses are linked to a multitude of human illnesses and can disseminate widely in
urbanized environments causing global adverse impacts on communities and healthcare …

More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

COVID-19 vaccines are indispensable, with the number of cases and mortality still rising,
and currently no medicines are routinely available for reducing morbidity and mortality, apart …

ABSTRACT Introduction: Human adenovirus (HAdV)-derived vectors have been used in
numerous pre-clinical and clinical trials during the last 40 years. Current research in HAdV …

The concept of viral vector-based vaccine was introduced in 1972 by Jackson et al and in
1982 Moss et al introduced the use of vaccinia virus as a transient gene expression vector …

Animals found in close proximity to humans in low-and middle-income countries (LMICs)
harbor many pathogens capable of infecting humans, transmissible via their feces. Contact …