Periodontitis is a common disorder affecting> 40% of adults in the United States. Globally,
the severe form of the disease has a prevalence of 11%. In advanced cases, periodontitis …

To induce bone regeneration there is a complex cascade of growth factors. Growth factors
such as recombinant BMP-2, BMP-7, and PDGF are FDA-approved therapies in bone …

Periodontal disease (PD) is one of the most common inflammatory oral diseases, affecting
approximately 47% of adults aged 30 years or older in the United States. If not treated …

Background The aim of this systematic review was to compare clinical, radiographic and
patient‐reported outcomes (PROMs) in intra‐bony defects treated with regenerative surgery …

To date, the delivery of signaling molecules for bone regeneration has focused primarily on
factors that directly affect the bone formation pathways (osteoinduction) or that serve to …

The balance between bone resorption and bone formation is vital for maintenance and
regeneration of alveolar bone and supporting structures around teeth and dental implants …

Bone grafting is routinely performed in periodontology and oral surgery to fill bone voids.
While autogenous bone is considered the gold standard because of its regenerative …

Background Systematic reviews have established the short‐term improvements of
periodontal regenerative/reconstructive procedures compared to conventional surgical …

Aim: The use of recombinant human platelet-derived growth factor–BB (rhPDGF) has
received Food and Drug Administration approval for the treatment of periodontal and …

Background: Platelet‐rich fibrin (PRF) is a second‐generation platelet concentrate that
releases various growth factors that promote tissue regeneration. Metformin (MF), a member …