Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease, causing
progressive muscle wasting and eventual paralysis. A number of the cellular functions that …

V klinické praxi často dochází k nežádoucím účinkům léčiv v důsledku jejich špatného
dávkování. Těmto nežádoucím účinkům se dá předejít odhalením rychlosti jejich …

US10512698B2 - Method for genetic treatment using the AAV-XBP1s/GFP virus and use
thereof in the prevention and treatment of amyotrophic lateral sclerosis - Google Patents …

Protein quality control is essential for cellular homeostasis, and defects in the same result in
various pathological conditions such as neurodegenerative diseases and cancer …

The clinical manifestation of neurodegenerative diseases is initiated by the selective
alteration in the functionality of distinct neuronal populations. The pathology of many …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting
motoneurons in the brain and spinal cord leading to paralysis and death. Although the …

Amyotrophic lateral sclerosis (ALS) is a late‐onset and rapidly progressive
neurodegenerative disease in humans, which is characterised by the degeneration and loss …

The results of published studies with various neuroprotectors seeking to preserve motor
neuron function and improve survival in amyotrophic lateral sclerosis patients have poor …

There is no cure for chronic neurodegenerative diseases and disease-modifying therapies
are limited. In order to develop successful disease-modifying therapies the molecules and …

Las enfermedades neurodegenerativas más comunes en los seres humanos, tales como la
enfermedad de Alzheimer, la enfermedad de Parkinson, la enfermedad de Huntington, ELA …